TRIML2 and KRT24

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRIML2	KRT24
Description		tripartite motif family like 2	keratin 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Protein Ubiquitination Response To Retinoic Acid Innate Immune Response	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 25574032)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 30929738 31619474 31959851) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		46 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZFHX3	36 interacting genes: AARD ABI2 ABI3 AIRIM AMOT BFSP2 C1orf216 CCDC146 CCHCR1 HGS KRT1 KRT2 KRT20 KRT3 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT78 KRT79 KRT8 KRT80 KRT81 ODAD3 PCM1 PRPH RCOR3 SGF29 SNAPIN TCHP TRIML2 TSGA10IP TXLNA
Entrez ID		205860	192666
HPRD ID		08696	09668
Ensembl ID		ENSG00000179046	ENSG00000167916
Uniprot IDs		A0A804HJA0 B7ZLC3 Q8N7C3	Q2M2I5
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Protein Binding Supramolecular Fiber Organization Somite Specification Epithelial Cell Differentiation Cytoskeleton Morphogenesis Of An Epithelium Cytoskeleton Organization Organelle Organization Cellular Developmental Process Tissue Morphogenesis Segment Specification Somite Development Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion	Intermediate Filament Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Structural Constituent Of Cytoskeleton Cytosol Intermediate Filament Cytoskeleton Extracellular Exosome Actin-based Cell Projection Cytoskeleton Protein Binding Cornified Envelope SCAR Complex Centriole Structural Molecule Activity Peptide Cross-linking Regulation Of Cell Projection Assembly Cell Projection Organization Desmosome
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