TRIML2 and MBD3L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRIML2	MBD3L2
Description		tripartite motif family like 2	methyl-CpG binding domain protein 3 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Methyl-CpG Binding
	Biological Process	Protein Ubiquitination Response To Retinoic Acid Innate Immune Response	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation-dependent Constitutive Heterochromatin Formation Regulation Of Transcription By RNA Polymerase II Regulation Of Chromatin Organization
Pathways
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 25574032)
Interacting Genes		46 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZFHX3	12 interacting genes: CCDC136 GOLGA6L9 GPRASP2 KRT27 KRT34 KRTAP6-3 MBD2 MDFI POLD3 RUNDC3A SBK3 TRIML2
Entrez ID		205860	125997
HPRD ID		08696	12139
Ensembl ID		ENSG00000179046	ENSG00000230522
Uniprot IDs		A0A804HJA0 B7ZLC3 Q8N7C3	Q8NHZ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Protein Binding Supramolecular Fiber Organization Somite Specification Epithelial Cell Differentiation Cytoskeleton Morphogenesis Of An Epithelium Cytoskeleton Organization Organelle Organization Cellular Developmental Process Tissue Morphogenesis Segment Specification Somite Development Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion	Intermediate Filament
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