TRIML2 and KRT15

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRIML2	KRT15
Description		tripartite motif family like 2	keratin 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis Scaffold Protein Binding
	Biological Process	Protein Ubiquitination Response To Retinoic Acid Innate Immune Response	Morphogenesis Of An Epithelium Epidermis Development Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Polycystic ovary syndrome ( 25574032)
Interacting Genes		46 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZFHX3	144 interacting genes: ABI2 ABI3 ABLIM1 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5PO BEX2 C1orf216 CALCOCO1 CARD9 CATSPERT CCDC120 CCDC185 CCDC187 CCDC87 CCHCR1 CCNB1IP1 CCNC CDK18 CEP57 COX5B CREB5 CYTH4 DEPP1 DES DEUP1 DGCR6L DRC4 DTNB EFHC1 ENKD1 EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAPLN2 HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KDM1A KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT1 KRT18 KRT19 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RAMAC RCOR3 RHPN1 RIBC1 RIBC2 RNF6 RPP25 RSPH14 SGF29 SIRPA SMARCB1 SMARCD1 SMARCE1 SNAPIN SPG21 SSX2IP TBC1D21 TCHP TEKT4 TELO2 TIMM8A TLE5 TMSB4X TRIM42 TRIML2 TSG101 TTC23 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638 ZNF688
Entrez ID		205860	3866
HPRD ID		08696	01009
Ensembl ID		ENSG00000179046	ENSG00000171346
Uniprot IDs		A0A804HJA0 B7ZLC3 Q8N7C3	B3KVF5 P19012
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Protein Binding Supramolecular Fiber Organization Somite Specification Epithelial Cell Differentiation Cytoskeleton Morphogenesis Of An Epithelium Cytoskeleton Organization Organelle Organization Cellular Developmental Process Tissue Morphogenesis Segment Specification Somite Development Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Protein Binding Cytoskeleton Structural Constituent Of Cytoskeleton Microtubule-based Process Intermediate Filament Cytoskeleton Microtubule-based Movement Centrosome Axonemal A Tubule Inner Sheath Flagellated Sperm Motility Sperm Motility Intermediate Filament Polymerization Or Depolymerization Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Brahma Complex NpBAF Complex Establishment Of Cell Polarity Involved In Ameboidal Cell Migration RSC-type Complex Regulation Of Sister Chromatid Segregation NBAF Complex Cell Projection Microtubule Cytoskeleton Organization Motile Cilium Nucleosome Disassembly Microtubule Cilium Movement Sperm Mitochondrial Sheath Assembly Protein-DNA Complex Disassembly
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