AEN and RBMY1A1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		AEN	RBMY1A1
Description		apoptosis enhancing nuclease	RNA binding motif protein Y-linked family 1 member A1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus
	Molecular Function	Nucleic Acid Binding Nuclease Activity Exonuclease Activity DNA Exonuclease Activity Protein Binding Hydrolase Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	DNA Metabolic Process RNA Processing Apoptotic Process DNA Damage Response Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)
Interacting Genes		36 interacting genes: EMD EXOSC8 GNPTAB HAP1 HOMEZ IKZF1 KANK2 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF408 ZNF473	29 interacting genes: AEN APOBEC3C CBX2 CIRBP CLK3 DAAM2 DHX57 HBZ HNRNPK KHDRBS3 LMNTD2 LNX1 MYPOP PCDHB14 PRPF31 PRR3 RASD1 RBM3 RBMX RBMY1F RBMY1J SNRPA SRSF3 SRSF9 TERF1 TH TRA2B YTHDC1 ZNF317
Entrez ID		64782	5940
HPRD ID		08573	02450
Ensembl ID		ENSG00000181026	ENSG00000234414
Uniprot IDs		Q8WTP8	P0DJD3
PDB IDs			2FY1
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Identical Protein Binding Nucleus Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Zinc Ion Binding Regulation Of RNA Splicing Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Regulation Of Macromolecule Biosynthetic Process	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing Nucleic Acid Binding Regulation Of MRNA Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Binding MRNA Processing Positive Regulation Of RNA Splicing RNA Splicing RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Metabolic Process Positive Regulation Of MRNA Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome RNA Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleic Acid Metabolic Process Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Primary Metabolic Process Negative Regulation Of RNA Splicing Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleus Negative Regulation Of MRNA Metabolic Process Protein Domain Specific Binding Nucleoplasm Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Pre-mRNA Binding Negative Regulation Of Macromolecule Metabolic Process Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Gene Expression Nuclear Speck Protein Binding Negative Regulation Of Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere
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