AEN and MBNL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AEN	MBNL1
Gene Name		apoptosis enhancing nuclease	muscleblind-like splicing regulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Nucleus Nucleoplasm Cytoplasm Centrosome Cytoplasmic Stress Granule
	Molecular Function	Nucleic Acid Binding Exonuclease Activity	RNA Binding Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Selection Nervous System Development Skeletal Muscle Tissue Development RNA Splicing Embryonic Limb Morphogenesis Regulation Of RNA Splicing Myoblast Differentiation
Pathways
Drugs
Diseases
GWAS			Infantile hypertrophic pyloric stenosis ( 22306654)
Protein-Protein Interactions		33 interactors: AAMP AES EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SSX2IP TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473	9 interactors: ABI3BP AEN AES APP BIN1 DAB1 IDH3A ITSN2 ZNHIT3
Entrez ID		64782	4154
HPRD ID		08573	07355
Ensembl ID		ENSG00000181026	ENSG00000152601
Uniprot IDs		Q8WTP8	Q86VM6 Q9NR56
PDB IDs			3D2N 3D2Q 3D2S
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Negative Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing MRNA Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process MRNA Processing Positive Regulation Of Neutrophil Differentiation Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Androgen Secretion Regulation Of Viral Transcription Cellular Metabolic Process RNA Processing Negative Regulation Of Viral Process Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Estrogen Receptor Binding Regulation Of Wnt Signaling Pathway Response To Interleukin-1 Positive Regulation Of Anoikis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Binding Negative Regulation Of Nucleic Acid-templated Transcription Histone MRNA 3'-end Processing RNA Splicing Biosynthetic Process Intraciliary Transport Involved In Cilium Morphogenesis	Regulation Of Astrocyte Differentiation Regulation Of Glial Cell Differentiation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Regulation Of Gliogenesis Lipid Tube Assembly Cerebellum Structural Organization Synaptic Growth At Neuromuscular Junction Adult Locomotory Behavior Regulation Of Neuron Differentiation Collateral Sprouting In Absence Of Injury Lateral Motor Column Neuron Migration Dendrite Development Regulation Of Protein Binding Spinal Cord Motor Neuron Migration Positive Regulation Of Anoikis Endocytosis Positive Regulation Of Catalytic Activity Adult Behavior Radial Glia Guided Migration Of Purkinje Cell Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Neurogenesis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Neuron Differentiation Axon Choice Point Recognition Regulation Of Cell Development Locomotory Behavior Neuron Remodeling Positive Regulation Of Astrocyte Differentiation Regulation Of Binding
Tagcloud ?		abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal	arntl2 atlantic clock clocks cry1b cry2 cry3 cryptochrome gadus kaput minded morhua muscleblind myf5 npas1 npas2 nr1d1 nr1d2a ontogenesis oscillators per2a per2b rhythmicity rora synteny teleosts tetrapods timeless translocator
Tagcloud (Difference) ?		abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal	arntl2 atlantic clock clocks cry1b cry2 cry3 cryptochrome gadus kaput minded morhua muscleblind myf5 npas1 npas2 nr1d1 nr1d2a ontogenesis oscillators per2a per2b rhythmicity rora synteny teleosts tetrapods timeless translocator
Tagcloud (Intersection) ?