AEN and ZFP64

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AEN	ZFP64
Gene Name		apoptosis enhancing nuclease	ZFP64 zinc finger protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Nucleus
	Molecular Function	Nucleic Acid Binding Exonuclease Activity	DNA Binding Metal Ion Binding
	Biological Process	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis ( 17362836) Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		33 interactors: AAMP AES EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SSX2IP TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473	21 interactors: AEN BARD1 BEGAIN BYSL C14orf1 FAM124A FHL2 LMO2 LNX1 MAFB MFAP1 MTUS2 PBK PPARGC1B SETDB1 TLE1 TRIM41 UNC119 ZBTB9 ZNF513 ZNF70
Entrez ID		64782	55734
HPRD ID		08573	15728
Ensembl ID		ENSG00000181026	ENSG00000020256
Uniprot IDs		Q8WTP8	B3KQX0 Q9NPA5 Q9NTW7
PDB IDs			1X5W 2DMD
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Negative Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing MRNA Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process MRNA Processing Positive Regulation Of Neutrophil Differentiation Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Androgen Secretion Regulation Of Viral Transcription Cellular Metabolic Process RNA Processing Negative Regulation Of Viral Process Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Estrogen Receptor Binding Regulation Of Wnt Signaling Pathway Response To Interleukin-1 Positive Regulation Of Anoikis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Binding Negative Regulation Of Nucleic Acid-templated Transcription Histone MRNA 3'-end Processing RNA Splicing Biosynthetic Process Intraciliary Transport Involved In Cilium Morphogenesis	Transcription, DNA-templated Negative Regulation Of Erythrocyte Differentiation Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Myeloid Cell Differentiation Regulation Of Erythrocyte Differentiation Regulation Of Nitrogen Compound Metabolic Process Gene Expression Trabecula Morphogenesis Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Rhombomere 6 Development Macromolecule Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Gene Expression Negative Regulation Of Myeloid Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Brain Segmentation Atrial Cardiac Muscle Cell Development Cytokinesis, Completion Of Separation Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Blastocyst Development Metabolic Process Regulation Of Nucleic Acid-templated Transcription Rhombomere 5 Development Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Radiation Negative Regulation Of Protein Export From Nucleus Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Gene Expression Organ Development Mitotic Cytokinetic Process Protein K6-linked Ubiquitination Organ Morphogenesis Histone H3-K9 Trimethylation Visual Perception Sensory Perception Of Light Stimulus
Tagcloud ?		abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal	13q 17p 18q 22q 3p 4p 5q 9p dkk gastric heterozygosity hpp1 imc imcs instability intramucosal loh methylated methylations microsatellite mlh msi rassf2a runx3 sall4 sfrp1 smc smcs submucosal
Tagcloud (Difference) ?		abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal	13q 17p 18q 22q 3p 4p 5q 9p dkk gastric heterozygosity hpp1 imc imcs instability intramucosal loh methylated methylations microsatellite mlh msi rassf2a runx3 sall4 sfrp1 smc smcs submucosal
Tagcloud (Intersection) ?