DLG2 and KIF1B

Number of citations of the paper that reports this interaction (PMID 16637659)
18

Data Source:
HPRD (in vitro)

		DLG2	KIF1B
Gene Name		discs, large homolog 2 (Drosophila)	kinesin family member 1B
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Ionotropic Glutamate Receptor Complex Postsynaptic Density Membrane Basolateral Plasma Membrane Cell Junction Juxtaparanode Region Of Axon Postsynaptic Membrane	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection
	Molecular Function	Guanylate Kinase Activity Protein Binding Ionotropic Glutamate Receptor Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding
	Biological Process	Synaptic Transmission Nervous System Development Negative Regulation Of Phosphatase Activity Sensory Perception Of Pain Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Nucleotide Phosphorylation Receptor Localization To Synapse	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axon Cargo Transport Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport Mitochondrion Transport Along Microtubule
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Parkinson's disease ( 17052657) Phospholipid levels (plasma) ( 22359512) Protein quantitative trait loci ( 18464913) Wilms tumor ( 22544364)	Hepatocellular carcinoma ( 20676096) Mean platelet volume ( 22139419) Multiple sclerosis ( 18997785)
Protein-Protein Interactions		40 interactors: ABCA1 ATP2B2 ATP2B4 CACNG2 CNKSR2 CRIPT DLG1 DLG4 DLGAP1 ERBB4 FASLG FZD1 FZD4 FZD7 GLS2 GRID1 GRID2 GRIN1 GRIN2A GRIN2B GRIN2D GUCY1A2 KCNA4 KCNJ12 KCNJ2 KCNJ4 KHDRBS1 KIF1B LIN7A LRP2 MAP1A MAPK12 NLGN1 NLGN2 NLGN3 NOS1 SCN4A SCN5A SEMA4C WNT3A	16 interactors: ARHGAP1 BRCA1 CALM1 CHP1 CPEB1 DLG1 DLG2 DLG3 DLG4 EEF1A1 GIPC1 INADL SIAH1 SNTA1 STARD13 YWHAG
Entrez ID		1740	23095
HPRD ID		04663	05818
Ensembl ID		ENSG00000150672	ENSG00000054523
Uniprot IDs		B7Z2T4 E9PN83 Q15700	O60333
PDB IDs		2BYG 2HE2	2EH0
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Membrane Depolarization Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Membrane Potential Regulation Of Ion Transport Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Neuron-neuron Synaptic Transmission Neuromuscular Process Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Ion Transmembrane Transport Neurological System Process Regulation Of Signaling Glutamate Receptor Signaling Pathway Startle Response Ion Transport Regulation Of Synaptic Transmission Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Signal Transduction Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Sodium Ion Transmembrane Transport Nervous System Development Metal Ion Transport Transmembrane Transport Positive Regulation Of Membrane Potential Transport Negative Regulation Of Adrenergic Receptor Signaling Pathway Neuron Differentiation Cation Transmembrane Transport Protein Localization To Synapse Positive Regulation Of Transport Neurogenesis Behavior Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Regulation Of Receptor Activity Metencephalon Development Regulation Of Respiratory Gaseous Exchange Regulation Of Cellular Process Regulation Of Sodium Ion Transport Generation Of Neurons Postsynaptic Membrane Organization Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cell Morphogenesis Involved In Differentiation Postsynaptic Membrane Assembly	Receptor Localization To Synapse Protein Localization To Synapse Receptor Clustering Nucleotide Phosphorylation Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Signaling Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphatase Activity Membrane Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Negative Regulation Of Protein Metabolic Process Response To Stimulus Synaptic Transmission Regulation Of Dephosphorylation Regulation Of Sodium Ion Transmembrane Transport Regulation Of Signal Transduction Regulation Of Synaptic Plasticity Regulation Of Catalytic Activity Regulation Of Ion Transmembrane Transport Negative Regulation Of Phosphatase Activity Regulation Of Sodium Ion Transport Negative Regulation Of Dephosphorylation Cellular Response To Stimulus Cellular Protein Localization Regulation Of Cellular Protein Metabolic Process Cell-cell Signaling Regulation Of Cellular Process Signaling Cell Communication Regulation Of Protein Metabolic Process Regulation Of Ion Transport Regulation Of Synaptic Transmission Cellular Localization Signal Transduction Protein Localization To Membrane Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Protein Stability Intracellular Signal Transduction Regulation Of Ion Transmembrane Transporter Activity Axon Guidance Regulation Of Transmembrane Transporter Activity Protein Localization Cortical Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Protein Autophosphorylation Posttranscriptional Regulation Of Gene Expression Establishment Or Maintenance Of Cell Polarity Regulation Of Phosphorus Metabolic Process Regulation Of Cell Cycle Process
Tagcloud ?		17q12 apical basolateral defining disc discs dlg3 encodes germline guanylate homology identity imaginal lethal mediating member neoplastic oncogene organization originally overgrowth p55 phosphoprotein polarity q21 recessive segment similarity	clues depdc5 directions dp dq exome g1896a gwass hbv hepatocarcinogenesis hla hotspots htert integrations landscape mica mutational pnpla3 pose possibilities rtm204i rtm204v shall technologies threats throughput transitions underlined warrant
Tagcloud (Difference) ?		17q12 apical basolateral defining disc discs dlg3 encodes germline guanylate homology identity imaginal lethal mediating member neoplastic oncogene organization originally overgrowth p55 phosphoprotein polarity q21 recessive segment similarity	clues depdc5 directions dp dq exome g1896a gwass hbv hepatocarcinogenesis hla hotspots htert integrations landscape mica mutational pnpla3 pose possibilities rtm204i rtm204v shall technologies threats throughput transitions underlined warrant
Tagcloud (Intersection) ?