DLG2 and GRID1

Number of citations of the paper that reports this interaction (PMID 10234023)
12

Data Source:
HPRD (two hybrid)

		DLG2	GRID1
Gene Name		discs, large homolog 2 (Drosophila)	glutamate receptor, ionotropic, delta 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Ionotropic Glutamate Receptor Complex Postsynaptic Density Membrane Basolateral Plasma Membrane Cell Junction Juxtaparanode Region Of Axon Postsynaptic Membrane	Ionotropic Glutamate Receptor Complex Cell Junction Dendrite Postsynaptic Membrane Extracellular Vesicular Exosome
	Molecular Function	Guanylate Kinase Activity Protein Binding Ionotropic Glutamate Receptor Binding	Ionotropic Glutamate Receptor Activity Extracellular-glutamate-gated Ion Channel Activity
	Biological Process	Synaptic Transmission Nervous System Development Negative Regulation Of Phosphatase Activity Sensory Perception Of Pain Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Nucleotide Phosphorylation Receptor Localization To Synapse	Ion Transmembrane Transport Social Behavior Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Parkinson's disease ( 17052657) Phospholipid levels (plasma) ( 22359512) Protein quantitative trait loci ( 18464913) Wilms tumor ( 22544364)	Anorexia nervosa ( 23568457) Cardiac structure and function ( 19584346) Pancreatic cancer ( 23180869) Periodontal microbiota ( 22699663) Stearic acid (18:0) plasma levels ( 23362303)
Protein-Protein Interactions		40 interactors: ABCA1 ATP2B2 ATP2B4 CACNG2 CNKSR2 CRIPT DLG1 DLG4 DLGAP1 ERBB4 FASLG FZD1 FZD4 FZD7 GLS2 GRID1 GRID2 GRIN1 GRIN2A GRIN2B GRIN2D GUCY1A2 KCNA4 KCNJ12 KCNJ2 KCNJ4 KHDRBS1 KIF1B LIN7A LRP2 MAP1A MAPK12 NLGN1 NLGN2 NLGN3 NOS1 SCN4A SCN5A SEMA4C WNT3A	3 interactors: DLG2 EML1 GOPC
Entrez ID		1740	2894
HPRD ID		04663	17078
Ensembl ID		ENSG00000150672	ENSG00000182771
Uniprot IDs		B7Z2T4 E9PN83 Q15700	A8KAN9 Q9ULK0
PDB IDs		2BYG 2HE2
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Membrane Depolarization Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Membrane Potential Regulation Of Ion Transport Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Neuron-neuron Synaptic Transmission Neuromuscular Process Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Ion Transmembrane Transport Neurological System Process Regulation Of Signaling Glutamate Receptor Signaling Pathway Startle Response Ion Transport Regulation Of Synaptic Transmission Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Signal Transduction Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Sodium Ion Transmembrane Transport Nervous System Development Metal Ion Transport Transmembrane Transport Positive Regulation Of Membrane Potential Transport Negative Regulation Of Adrenergic Receptor Signaling Pathway Neuron Differentiation Cation Transmembrane Transport Protein Localization To Synapse Positive Regulation Of Transport Neurogenesis Behavior Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Regulation Of Receptor Activity Metencephalon Development Regulation Of Respiratory Gaseous Exchange Regulation Of Cellular Process Regulation Of Sodium Ion Transport Generation Of Neurons Postsynaptic Membrane Organization Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cell Morphogenesis Involved In Differentiation Postsynaptic Membrane Assembly	Cytoplasmic Sequestering Of CFTR Protein Negative Regulation Of Golgi To Plasma Membrane Protein Transport Receptor Localization To Synapse Regulation Of Golgi To Plasma Membrane Protein Transport Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Apical Protein Localization Protein Localization To Synapse Negative Regulation Of Protein Localization To Plasma Membrane Cytoplasmic Sequestering Of Protein Asymmetric Protein Localization Spermatid Nucleus Differentiation Golgi To Plasma Membrane Transport Mitotic Spindle Organization Regulation Of Establishment Of Protein Localization To Plasma Membrane
Tagcloud ?		17q12 apical basolateral defining disc discs dlg3 encodes germline guanylate homology identity imaginal lethal mediating member neoplastic oncogene organization originally overgrowth p55 phosphoprotein polarity q21 recessive segment similarity
Tagcloud (Difference) ?		17q12 apical basolateral defining disc discs dlg3 encodes germline guanylate homology identity imaginal lethal mediating member neoplastic oncogene organization originally overgrowth p55 phosphoprotein polarity q21 recessive segment similarity
Tagcloud (Intersection) ?