DLG2 and CRIPT

Number of citations of the paper that reports this interaction (PMID 9581762)
35

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		DLG2	CRIPT
Gene Name		discs, large homolog 2 (Drosophila)	cysteine-rich PDZ-binding protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Ionotropic Glutamate Receptor Complex Postsynaptic Density Membrane Basolateral Plasma Membrane Cell Junction Juxtaparanode Region Of Axon Postsynaptic Membrane	Nucleus Nucleolus Cytoplasm Postsynaptic Density Cell Junction Dendrite Neuronal Cell Body Dendritic Spine Dendritic Shaft
	Molecular Function	Guanylate Kinase Activity Protein Binding Ionotropic Glutamate Receptor Binding	Protein Binding Microtubule Binding PDZ Domain Binding Protein Complex Binding
	Biological Process	Synaptic Transmission Nervous System Development Negative Regulation Of Phosphatase Activity Sensory Perception Of Pain Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Nucleotide Phosphorylation Receptor Localization To Synapse	Cytoplasmic Microtubule Organization Protein Localization To Microtubule Establishment Of Protein Localization Regulation Of Postsynaptic Density Protein 95 Clustering
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Parkinson's disease ( 17052657) Phospholipid levels (plasma) ( 22359512) Protein quantitative trait loci ( 18464913) Wilms tumor ( 22544364)	Height ( 20966902)
Protein-Protein Interactions		40 interactors: ABCA1 ATP2B2 ATP2B4 CACNG2 CNKSR2 CRIPT DLG1 DLG4 DLGAP1 ERBB4 FASLG FZD1 FZD4 FZD7 GLS2 GRID1 GRID2 GRIN1 GRIN2A GRIN2B GRIN2D GUCY1A2 KCNA4 KCNJ12 KCNJ2 KCNJ4 KHDRBS1 KIF1B LIN7A LRP2 MAP1A MAPK12 NLGN1 NLGN2 NLGN3 NOS1 SCN4A SCN5A SEMA4C WNT3A	7 interactors: DLG1 DLG2 DLG3 DLG4 INADL TUBB UBQLN4
Entrez ID		1740	9419
HPRD ID		04663	05208
Ensembl ID		ENSG00000150672	ENSG00000119878
Uniprot IDs		B7Z2T4 E9PN83 Q15700	Q9P021
PDB IDs		2BYG 2HE2
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Membrane Depolarization Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Membrane Potential Regulation Of Ion Transport Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Neuron-neuron Synaptic Transmission Neuromuscular Process Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Ion Transmembrane Transport Neurological System Process Regulation Of Signaling Glutamate Receptor Signaling Pathway Startle Response Ion Transport Regulation Of Synaptic Transmission Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Signal Transduction Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Sodium Ion Transmembrane Transport Nervous System Development Metal Ion Transport Transmembrane Transport Positive Regulation Of Membrane Potential Transport Negative Regulation Of Adrenergic Receptor Signaling Pathway Neuron Differentiation Cation Transmembrane Transport Protein Localization To Synapse Positive Regulation Of Transport Neurogenesis Behavior Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Regulation Of Receptor Activity Metencephalon Development Regulation Of Respiratory Gaseous Exchange Regulation Of Cellular Process Regulation Of Sodium Ion Transport Generation Of Neurons Postsynaptic Membrane Organization Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cell Morphogenesis Involved In Differentiation Postsynaptic Membrane Assembly	Receptor Localization To Synapse Protein Localization To Synapse Receptor Clustering Nucleotide Phosphorylation Establishment Or Maintenance Of Apical/basal Cell Polarity Protein Localization To Membrane Nucleotide Metabolic Process Synaptic Transmission Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Cell Polarity Nucleobase-containing Small Molecule Metabolic Process Cortical Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Membrane Organization Cell-cell Signaling Tight Junction Assembly Organophosphate Metabolic Process Negative Regulation Of Phosphatase Activity Axon Guidance Negative Regulation Of Dephosphorylation Cellular Localization Apical Junction Assembly Cellular Protein Localization Axonogenesis Regulation Of Phosphatase Activity Axon Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Cell-cell Junction Assembly Chemotaxis Regulation Of Dephosphorylation Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Phosphorylation Cellular Component Assembly Protein Localization Neuron Projection Development T Cell Cytokine Production Cell Projection Morphogenesis Cell Junction Assembly Cell Part Morphogenesis Cell-cell Junction Organization Hard Palate Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Neuron Development Nervous System Development Negative Regulation Of Receptor Internalization Leukocyte Mediated Immunity
Tagcloud ?		17q12 apical basolateral defining disc discs dlg3 encodes germline guanylate homology identity imaginal lethal mediating member neoplastic oncogene organization originally overgrowth p55 phosphoprotein polarity q21 recessive segment similarity
Tagcloud (Difference) ?		17q12 apical basolateral defining disc discs dlg3 encodes germline guanylate homology identity imaginal lethal mediating member neoplastic oncogene organization originally overgrowth p55 phosphoprotein polarity q21 recessive segment similarity
Tagcloud (Intersection) ?