FAM171B and MPP3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		FAM171B	MPP3
Description		family with sequence similarity 171 member B	MAGUK p55 scaffold protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Synapse	Plasma Membrane Cell-cell Junction Adherens Junction Membrane Apical Plasma Membrane Anchoring Junction
	Molecular Function		Protein Binding PDZ Domain Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Microalbuminuria ( 26631737) Urinary albumin-to-creatinine ratio ( 26631737) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)	HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068)
Interacting Genes		2 interacting genes: CAMK2D MPP3	37 interacting genes: APP ARL2BP BTBD1 CADM1 CCDC137 CRABP1 ERBIN EZR FAM171B FBXO7 GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A MCM2 MDH1 NOA1 PKNOX1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TIRAP TMEM37 TRAF2 TRIM41 ZNF655 ZPR1
Entrez ID		165215	4356
HPRD ID		13907	03069
Ensembl ID		ENSG00000144369	ENSG00000161647
Uniprot IDs		Q6P995	D3DX46 Q13368
PDB IDs
Enriched GO Terms of Interacting Partners?		Sodium Channel Inhibitor Activity Negative Regulation Of Sodium Ion Transport Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium- And Calmodulin-dependent Protein Kinase Complex Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Titin Binding Regulation Of Relaxation Of Muscle Relaxation Of Cardiac Muscle Regulation Of Relaxation Of Cardiac Muscle Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Dendritic Microtubule Regulation Of Dendritic Spine Maintenance Positive Regulation Of Dendritic Spine Maintenance Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Relaxation Of Muscle Calcium/calmodulin-dependent Protein Kinase Activity Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of The Force Of Heart Contraction Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Cardiac Muscle Hypertrophy Actin-mediated Cell Contraction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Heart Rate By Cardiac Conduction Sarcoplasmic Reticulum Membrane Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Dendritic Shaft Regulation Of Membrane Depolarization Regulation Of Cardiac Muscle Cell Apoptotic Process Cardiac Conduction Long-term Synaptic Potentiation
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