CYP2C8 and APOE

  • Number of citations of the paper that reports this interaction (PMID 21163940)
  • 13
  • Data Source:
  • BioGRID (two hybrid)

CYP2C8

APOE

Gene Name cytochrome P450, family 2, subfamily C, polypeptide 8 apolipoprotein E
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immune response to smallpox vaccine (IL-6) ( 22542470)
  • Osteonecrosis of the jaw ( 18594024)
  • Response to clopidogrel therapy ( 19706858)
  • Warfarin maintenance dose ( 23755828)
Protein-Protein Interactions 11 interactors: A2M APOE BLMH DNAJB1 ECSIT EXOC6 IFIT3 LONP1 MAST1 PSEN1 RNF32 54 interactors: A2M ACTG1 ALB ANKH APP ARFGAP1 C19orf52 CDC37 CNTF CSNK2A1 CTSB CYP2C18 CYP2C8 ECSIT ELAVL1 EPN2 FARSA FBXL12 FOXG1 FXYD7 GCDH HTRA1 IFIT3 IFIT5 IQSEC1 LCAT LDLR LONP1 LOXL4 LRP1 LRP2 LRP8 MAP2 MAPT MAST1 MID1IP1 NEFM NOS3 PCMT1 PDCD4 PLEKHA6 PLTP PRAM1 PRDX2 PRNP PSEN1 RHEB RNF32 RPL4 SCARB1 ST13 TYRO3 VLDLR ZNF558
Entrez ID 1558 348
HPRD ID 03083 00135
Ensembl ID ENSG00000138115 ENSG00000130203
Uniprot IDs B7Z1F5 P10632 P02649
PDB IDs 1PQ2 2NNH 2NNI 2NNJ 2VN0 1B68 1BZ4 1EA8 1GS9 1H7I 1LE2 1LE4 1LPE 1NFN 1NFO 1OEF 1OEG 1OR2 1OR3 2KC3 2KNY 2L7B
Enriched GO Terms of Interacting Partners?
Tagcloud ?
allele  apolipoprotein  associations  cardiotoxicity  commonly  comt  conform  epsilon4  failed  fatigue  genetic  genotype  guidelines  il6  impairment  listed  lle655val  met  neuropathy  polymorphisms  reporting  strega  systematic  toxicities  transparent  underlying  val  variant  variants 
aa  adenovirus  agreement  amyloid  amyloids  apoe3  apoe4  apoj  apolipoprotein  apolipoproteins  appear  cerebral  characterize  deficient  define  deposition  deposits  fibril  fibrillogenesis  fibrils  fragment  greatest  heterozygous  injected  lacking  lipoproteins  promoting  restored  utilized 
Tagcloud (Difference) ?
allele  associations  cardiotoxicity  commonly  comt  conform  epsilon4  failed  fatigue  genetic  genotype  guidelines  il6  impairment  listed  lle655val  met  neuropathy  polymorphisms  reporting  strega  systematic  toxicities  transparent  underlying  val  variant  variants 
aa  adenovirus  agreement  amyloid  amyloids  apoe3  apoe4  apoj  apolipoproteins  appear  cerebral  characterize  deficient  define  deposition  deposits  fibril  fibrillogenesis  fibrils  fragment  greatest  heterozygous  injected  lacking  lipoproteins  promoting  restored  utilized 
Tagcloud (Intersection) ?
apolipoprotein