CYB561 and LPAR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYB561	LPAR3
Description		cytochrome b561	lysophosphatidic acid receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Membrane Cytoplasmic Vesicle Chromaffin Granule Membrane	Cytoplasm Plasma Membrane Cilium Membrane Axon Synapse
	Molecular Function	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Monodehydroascorbate Reductase Activity	G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity Protein Binding Phospholipid Binding Lipid Binding Lysophosphatidic Acid Receptor Activity
	Biological Process	Intracellular Iron Ion Homeostasis Electron Transport Chain Ascorbate Homeostasis	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemical Synaptic Transmission Gene Expression Bleb Assembly Positive Regulation Of MAPK Cascade Collateral Sprouting Positive Regulation Of Collateral Sprouting Positive Regulation Of Calcium Ion Transport
Pathways			G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diastolic blood pressure ( 28739976)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Dental caries ( 23064961) Femur bone mineral density x serum urate levels interaction ( 34046847) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		60 interacting genes: ANKRD46 AQP6 BEST2 BET1 BIK BNIP1 CD79A CDIPT CLDN9 CMTM2 CREB3 DARS2 EBP EDA EFNA5 EHHADH ERG28 ERGIC3 FAM209A FKBP8 GGT7 GIMAP5 GOSR2 GPR152 GPX8 HMOX1 LHFPL5 LMNA LPAR3 OPRM1 ORMDL2 PLP2 REEP6 RNF5 SCD SEC22A SERP2 SLC19A3 SLC35H1 SLC38A7 SLC39A1 SLC39A2 SMIM1 SSMEM1 STX3 SYNJ2BP TM4SF18 TMEM11 TMEM128 TMEM14B TMEM179B TMEM242 TMEM65 TMPPE TREX1 TSNARE1 UBE2J1 VAPA VAPB ZDHHC7	61 interacting genes: APP AQP6 ARL13B ASZ1 BCL2L13 C16orf54 CD53 CD74 CD79A CLDN2 CLDN7 CLDN9 CLEC12B CPLX4 CREB3L1 CYB561 CYBRD1 EDA ELOVL4 ERGIC3 FAM209A FAM210B FFAR2 FNDC9 GJB5 GNAI2 GORAB GPX8 HSD17B13 JAGN1 KCNC1 KCNJ6 LEPROTL1 LHFPL5 LIME1 LMNA MFF MGST3 MRM1 MS4A4A MUC1 NDUFAF2 OPRM1 PGRMC2 RELL2 RETREG3 SCN3B SGMS2 SHISAL1 SLC10A6 SLC16A2 SLC35H1 TFEC THAP4 TMEM14B TMEM237 TMEM31 TMEM41A TMEM52B TMEM70 TMEM79
Entrez ID		1534	23566
HPRD ID		02485	05486
Ensembl ID		ENSG00000008283	ENSG00000171517
Uniprot IDs		B3KTA1 J3QRH5 P49447	Q9UBY5
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Membrane Fusion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Binding Organelle Membrane Fusion FFAT Motif Binding Mitochondrial Membrane Golgi Vesicle Transport Endoplasmic Reticulum Organization Membrane Organization Organelle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum Localization Membrane Docking Vesicle Fusion Lipid Biosynthetic Process Host-mediated Activation Of Viral Genome Replication Positive Regulation Of Collateral Sprouting Host-mediated Perturbation Of Viral Genome Replication Progesterone Receptor Signaling Pathway Vesicle Organization	Membrane Protein Binding Negative Regulation Of Peptide Secretion Negative Regulation Of Secretion Ascorbate Homeostasis Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules B Cell Receptor Complex Transmembrane Monodehydroascorbate Reductase Activity Negative Regulation Of Protein Secretion Negative Regulation Of Secretion By Cell
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