CYB561 and EDA

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CYB561	EDA
Gene Name		cytochrome b561	ectodysplasin A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Region Collagen Trimer Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	Ferric-chelate Reductase Activity Transmembrane Electron Transfer Carrier Metal Ion Binding	Receptor Binding Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	Electron Transport Chain Transmembrane Transport	Immune Response Cell-matrix Adhesion Signal Transduction Ectoderm Development Gene Expression Cell Differentiation Positive Regulation Of NF-kappaB Import Into Nucleus Odontogenesis Of Dentin-containing Tooth Pigmentation Positive Regulation Of NF-kappaB Transcription Factor Activity Salivary Gland Cavitation Hair Follicle Placode Formation Trachea Gland Development Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
Protein-Protein Interactions		2 interactors: EDA RNF5	15 interactors: ATP6V0C CYB561 DOLK EDA2R EDAR EMP3 FURIN GIMAP5 LEPROTL1 MAL NIPAL3 OSTC OSTCP1 PLN SEC22A
Entrez ID		1534	1896
HPRD ID		02485	02347
Ensembl ID		ENSG00000008283	ENSG00000158813
Uniprot IDs		B3KTA1 F5H757 J3QKN3 J3QS47 P49447	Q92838
PDB IDs			1RJ7 1RJ8
Enriched GO Terms of Interacting Partners?		ER-associated Misfolded Protein Catabolic Process Trachea Gland Development Salivary Gland Cavitation Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Regulation Of Autophagic Vacuole Assembly Response To Misfolded Protein Hair Follicle Placode Formation Regulation Of Vacuole Organization Positive Regulation Of NF-kappaB Import Into Nucleus Protein Destabilization Ectoderm Development Trachea Development Protein K63-linked Ubiquitination Negative Regulation Of Autophagy Protein K48-linked Ubiquitination Positive Regulation Of Transcription Factor Import Into Nucleus ER-associated Ubiquitin-dependent Protein Catabolic Process Regulation Of NF-kappaB Import Into Nucleus Salivary Gland Morphogenesis Salivary Gland Development Exocrine System Development Regulation Of Transcription Factor Import Into Nucleus Hair Follicle Development Positive Regulation Of Protein Import Into Nucleus Hair Cycle Process Odontogenesis Of Dentin-containing Tooth Hair Cycle Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Regulation Of Autophagy Cellular Response To Topologically Incorrect Protein Pigmentation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Odontogenesis Regulation Of Protein Stability Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Intracellular Protein Transport Gland Morphogenesis Tube Formation Regulation Of Protein Import Into Nucleus Cell-matrix Adhesion Protein Polyubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell-substrate Adhesion Regulation Of Canonical Wnt Signaling Pathway	Positive Regulation Of Interleukin-15 Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Cytotoxic T Cell Differentiation Negative Regulation Of Calcium-transporting ATPase Activity TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Dolichyl Monophosphate Biosynthetic Process Negative Regulation Of Hydrolase Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Nerve Growth Factor Production Negative Regulation Of Calcium Ion Binding Regulation Of The Force Of Heart Contraction By Cardiac Conduction Protein N-linked Glycosylation Via Asparagine Cell Death Death Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Membrane Raft Polarization Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of Receptor Catabolic Process Adrenergic Receptor Signaling Pathway Involved In Heart Process Protein N-linked Glycosylation Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Nerve Growth Factor Processing G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Membrane Raft Localization Dolichyl Diphosphate Biosynthetic Process Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Calcium Ion Import Negative Regulation Of Transforming Growth Factor Beta Production Ectodermal Cell Differentiation Regulation Of JNK Cascade Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Salivary Gland Cavitation Regulation Of Stress-activated MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of ATPase Activity Regulation Of Relaxation Of Muscle Vesicle Fusion With Golgi Apparatus Regulation Of Cardiac Muscle Cell Membrane Potential Post-translational Protein Modification Transport
Tagcloud ?			amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls seem showing sweating tonic unrelated weakness
Tagcloud (Difference) ?			amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls seem showing sweating tonic unrelated weakness
Tagcloud (Intersection) ?