CYB561 and RNF5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CYB561	RNF5
Gene Name		cytochrome b561	ring finger protein 5, E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Ferric-chelate Reductase Activity Transmembrane Electron Transfer Carrier Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Electron Transport Chain Transmembrane Transport	Response To Bacterium Negative Regulation Of Autophagy Protein Destabilization Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination ER-associated Misfolded Protein Catabolic Process Regulation Of Autophagic Vacuole Assembly
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		2 interactors: EDA RNF5	32 interactors: ABHD16A CFTR CYB561 CYB561A3 FHOD1 INSIG2 JKAMP MAVS MPDZ PXN RNF185 SEC22A SLC1A1 SLC38A7 TGFBR1 TMEM242 TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G2 UBE2K UBE2N UBE2U UBE2V1 UBE2W UBE2Z YIPF2
Entrez ID		1534	6048
HPRD ID		02485	04057
Ensembl ID		ENSG00000008283	ENSG00000204308
Uniprot IDs		B3KTA1 F5H757 J3QKN3 J3QS47 P49447	Q99942
PDB IDs
Enriched GO Terms of Interacting Partners?		ER-associated Misfolded Protein Catabolic Process Trachea Gland Development Salivary Gland Cavitation Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Regulation Of Autophagic Vacuole Assembly Response To Misfolded Protein Hair Follicle Placode Formation Regulation Of Vacuole Organization Positive Regulation Of NF-kappaB Import Into Nucleus Protein Destabilization Ectoderm Development Trachea Development Protein K63-linked Ubiquitination Negative Regulation Of Autophagy Protein K48-linked Ubiquitination Positive Regulation Of Transcription Factor Import Into Nucleus ER-associated Ubiquitin-dependent Protein Catabolic Process Regulation Of NF-kappaB Import Into Nucleus Salivary Gland Morphogenesis Salivary Gland Development Exocrine System Development Regulation Of Transcription Factor Import Into Nucleus Hair Follicle Development Positive Regulation Of Protein Import Into Nucleus Hair Cycle Process Odontogenesis Of Dentin-containing Tooth Hair Cycle Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Regulation Of Autophagy Cellular Response To Topologically Incorrect Protein Pigmentation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Odontogenesis Regulation Of Protein Stability Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Intracellular Protein Transport Gland Morphogenesis Tube Formation Regulation Of Protein Import Into Nucleus Cell-matrix Adhesion Protein Polyubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell-substrate Adhesion Regulation Of Canonical Wnt Signaling Pathway	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Activation Of Innate Immune Response Protein K63-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Positive Regulation Of Innate Immune Response Cellular Protein Modification Process Regulation Of Innate Immune Response Cellular Macromolecule Catabolic Process Toll-like Receptor 4 Signaling Pathway Cellular Protein Metabolic Process Cellular Response To Stress Toll-like Receptor Signaling Pathway Proteolysis Immune Response-regulating Signaling Pathway Protein Metabolic Process Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Protein Ubiquitination Catabolic Process Positive Regulation Of Immune Response Histone Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Monoubiquitination Response To Organic Substance Negative Regulation Of Type I Interferon Production ISG15-protein Conjugation Aspartate Transport Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Innate Immune Response Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Organic Substance TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Immune Response Cellular Response To Transforming Growth Factor Beta Stimulus MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway
Tagcloud ?			adapt autoadaptive built cleared clients deploys dislocation dislocon dislocons engage erad folding herp hrd1 interrupt ligases machineries misfolded p97 perturbation polyubiquitylation preempt proteasomal proteostasis relay relies tuning turnover ubc6e
Tagcloud (Difference) ?			adapt autoadaptive built cleared clients deploys dislocation dislocon dislocons engage erad folding herp hrd1 interrupt ligases machineries misfolded p97 perturbation polyubiquitylation preempt proteasomal proteostasis relay relies tuning turnover ubc6e
Tagcloud (Intersection) ?