LPAR3

Gene Name		lysophosphatidic acid receptor 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Axon
	Molecular Function	G-protein Alpha-subunit Binding G-protein Coupled Receptor Activity Phospholipid Binding Lipid Binding Lysophosphatidic Acid Receptor Activity
	Biological Process	Activation Of MAPK Activity G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission Bleb Assembly Positive Regulation Of Collateral Sprouting Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Positive Regulation Of Calcium Ion Transport
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Dental caries ( 23064961)
Protein-protein Interactions		2 interactors: APP GNAI2
Entrez ID		23566
HPRD ID		05486
Ensembl ID		ENSG00000171517
Uniprot IDs		Q9UBY5
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Activation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Blood Coagulation Hemostasis Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Regulation Of Body Fluid Levels Wound Healing Neuron Remodeling Cell Activation Response To Wounding Regulation Of Protein Kinase Activity Adenosine Receptor Signaling Pathway Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity G-protein Coupled Acetylcholine Receptor Signaling Pathway Cellular Copper Ion Homeostasis Negative Regulation Of Adenylate Cyclase Activity Copper Ion Homeostasis Suckling Behavior Negative Regulation Of Lyase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of CAMP Biosynthetic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Gamma-aminobutyric Acid Signaling Pathway Negative Regulation Of CAMP Metabolic Process Positive Regulation Of Protein Metabolic Process Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Regulation Of Phosphorylation Negative Regulation Of Nucleotide Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition
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