CYB561 and BNIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYB561	BNIP1
Description		cytochrome b561	BCL2 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Membrane Cytoplasmic Vesicle Chromaffin Granule Membrane	Nuclear Envelope Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane COPI-coated Vesicle SNARE Complex Mitochondrial Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Monodehydroascorbate Reductase Activity	SNAP Receptor Activity Protein Binding Calcium-induced Calcium Release Activity
	Biological Process	Intracellular Iron Ion Homeostasis Electron Transport Chain Ascorbate Homeostasis	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Apoptotic Process Endoplasmic Reticulum Organization Response To Activity Vesicle-mediated Transport Endoplasmic Reticulum Membrane Fusion Calcium-mediated Signaling Response To Starvation Negative Regulation Of Apoptotic Process Response To Oxygen-glucose Deprivation Execution Phase Of Apoptosis Apoptotic Process In Response To Mitochondrial Fragmentation
Pathways			COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diastolic blood pressure ( 28739976)	Glaucoma (primary open-angle) ( 29891935) Infantile hypertrophic pyloric stenosis ( 22306654) PR interval ( 30046033 30679814 32439900) Pulse pressure ( 30578418)
Interacting Genes		60 interacting genes: ANKRD46 AQP6 BEST2 BET1 BIK BNIP1 CD79A CDIPT CLDN9 CMTM2 CREB3 DARS2 EBP EDA EFNA5 EHHADH ERG28 ERGIC3 FAM209A FKBP8 GGT7 GIMAP5 GOSR2 GPR152 GPX8 HMOX1 LHFPL5 LMNA LPAR3 OPRM1 ORMDL2 PLP2 REEP6 RNF5 SCD SEC22A SERP2 SLC19A3 SLC35H1 SLC38A7 SLC39A1 SLC39A2 SMIM1 SSMEM1 STX3 SYNJ2BP TM4SF18 TMEM11 TMEM128 TMEM14B TMEM179B TMEM242 TMEM65 TMPPE TREX1 TSNARE1 UBE2J1 VAPA VAPB ZDHHC7	25 interacting genes: APP BCL2 BCL2L1 CYB561 ELOVL4 ERBB2 FAM174A GPR35 HSD17B11 JAGN1 MARCHF5 NAPA NCBP1 PTGER4 RETREG3 SCN3B SLC7A14 STOM STX18 STX1A TM4SF19 TMEM31 TMX2 TSHR VMA21
Entrez ID		1534	662
HPRD ID		02485	04480
Ensembl ID		ENSG00000008283	ENSG00000113734
Uniprot IDs		B3KTA1 J3QRH5 P49447	Q12981
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Membrane Fusion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Binding Organelle Membrane Fusion FFAT Motif Binding Mitochondrial Membrane Golgi Vesicle Transport Endoplasmic Reticulum Organization Membrane Organization Organelle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum Localization Membrane Docking Vesicle Fusion Lipid Biosynthetic Process Host-mediated Activation Of Viral Genome Replication Positive Regulation Of Collateral Sprouting Host-mediated Perturbation Of Viral Genome Replication Progesterone Receptor Signaling Pathway Vesicle Organization	Membrane Endoplasmic Reticulum Dendritic Cell Apoptotic Process Synaptobrevin 2-SNAP-25-syntaxin-1a Complex BH3 Domain Binding Regulation Of Protein Localization Negative Regulation Of Dendritic Cell Apoptotic Process Bcl-2 Family Protein Complex Regulation Of Cellular Component Organization Regulation Of Cellular Localization Endoplasmic Reticulum Membrane Regulation Of Synaptic Vesicle Priming Regulation Of Biological Quality Cytoplasmic Vesicle Regulation Of Monoatomic Ion Transport Regulation Of Transport Negative Regulation Of Anoikis Regulation Of Membrane Potential Programmed Cell Death Involved In Cell Development Release Of Cytochrome C From Mitochondria Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Establishment Of Protein Localization Amylin Binding Neuron Maturation Positive Regulation Of Toll Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Retinal Cell Programmed Cell Death Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Cellular PH Reduction Leukocyte Proliferation Mononuclear Cell Proliferation Myelin Sheath Regulation Of Anoikis Negative Regulation Of Calcium Ion Transmembrane Transport Apoptotic Process In Bone Marrow Cell Positive Regulation Of Protein Targeting To Membrane Regulation Of Protein Targeting To Membrane Positive Regulation Of RNA Binding Negative Regulation Of Eosinophil Extravasation SNAP Receptor Activity Presynaptic Active Zone Membrane Myosin Head/neck Binding
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