CYB561 and REEP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYB561	REEP6
Description		cytochrome b561	receptor accessory protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Membrane Cytoplasmic Vesicle Chromaffin Granule Membrane	Photoreceptor Inner Segment Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Monodehydroascorbate Reductase Activity	Protein Binding
	Biological Process	Intracellular Iron Ion Homeostasis Electron Transport Chain Ascorbate Homeostasis	Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Detection Of Light Stimulus Involved In Visual Perception
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diastolic blood pressure ( 28739976)
Interacting Genes		60 interacting genes: ANKRD46 AQP6 BEST2 BET1 BIK BNIP1 CD79A CDIPT CLDN9 CMTM2 CREB3 DARS2 EBP EDA EFNA5 EHHADH ERG28 ERGIC3 FAM209A FKBP8 GGT7 GIMAP5 GOSR2 GPR152 GPX8 HMOX1 LHFPL5 LMNA LPAR3 OPRM1 ORMDL2 PLP2 REEP6 RNF5 SCD SEC22A SERP2 SLC19A3 SLC35H1 SLC38A7 SLC39A1 SLC39A2 SMIM1 SSMEM1 STX3 SYNJ2BP TM4SF18 TMEM11 TMEM128 TMEM14B TMEM179B TMEM242 TMEM65 TMPPE TREX1 TSNARE1 UBE2J1 VAPA VAPB ZDHHC7	46 interacting genes: AQP6 ARL6IP1 ATP5PF BIK CD79A CDC37 CERT1 COQ8A CYB561 CYB5R3 EBAG9 FHIP1B GJA8 GORASP2 GPR152 HMBOX1 HSD17B13 KRTAP3-1 LEPROTL1 LITAF LMNA LNX1 MIEF2 NDRG4 NTAQ1 PICK1 PTPN9 RPS20 SDCBP SLC30A8 SNX1 SNX11 SNX15 SNX8 SPG21 STING1 SYT16 TIMMDC1 TLCD4 TMED8 TMEM143 TMPPE TNS2 TXN2 WIPI2 ZFYVE21
Entrez ID		1534	92840
HPRD ID		02485	16629
Ensembl ID		ENSG00000008283	ENSG00000115255
Uniprot IDs		B3KTA1 J3QRH5 P49447	A0A1L5BXV2 Q96HR9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Membrane Fusion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Binding Organelle Membrane Fusion FFAT Motif Binding Mitochondrial Membrane Golgi Vesicle Transport Endoplasmic Reticulum Organization Membrane Organization Organelle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum Localization Membrane Docking Vesicle Fusion Lipid Biosynthetic Process Host-mediated Activation Of Viral Genome Replication Positive Regulation Of Collateral Sprouting Host-mediated Perturbation Of Viral Genome Replication Progesterone Receptor Signaling Pathway Vesicle Organization	Lipid Binding Establishment Of Protein Localization Identical Protein Binding Membrane
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