LPAR3 and TFEC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LPAR3	TFEC
Description		lysophosphatidic acid receptor 3	transcription factor EC
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cilium Membrane Axon Synapse	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity Protein Binding Phospholipid Binding Lipid Binding Lysophosphatidic Acid Receptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemical Synaptic Transmission Gene Expression Bleb Assembly Positive Regulation Of MAPK Cascade Collateral Sprouting Positive Regulation Of Collateral Sprouting Positive Regulation Of Calcium Ion Transport	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cellular Response To Heat Positive Regulation Of Transcription By RNA Polymerase II
Pathways		G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors	Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Dental caries ( 23064961) Femur bone mineral density x serum urate levels interaction ( 34046847) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)	Body mass index ( 28892062) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 28552196) Intraocular pressure ( 29235454 29617998 29785010) Number of sexual partners ( 30643258) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189) Tonsillectomy ( 27182965 28928442)
Interacting Genes		61 interacting genes: APP AQP6 ARL13B ASZ1 BCL2L13 C16orf54 CD53 CD74 CD79A CLDN2 CLDN7 CLDN9 CLEC12B CPLX4 CREB3L1 CYB561 CYBRD1 EDA ELOVL4 ERGIC3 FAM209A FAM210B FFAR2 FNDC9 GJB5 GNAI2 GORAB GPX8 HSD17B13 JAGN1 KCNC1 KCNJ6 LEPROTL1 LHFPL5 LIME1 LMNA MFF MGST3 MRM1 MS4A4A MUC1 NDUFAF2 OPRM1 PGRMC2 RELL2 RETREG3 SCN3B SGMS2 SHISAL1 SLC10A6 SLC16A2 SLC35H1 TFEC THAP4 TMEM14B TMEM237 TMEM31 TMEM41A TMEM52B TMEM70 TMEM79	11 interacting genes: DCK DEFB127 HNRNPA1 LPAR3 MITF NAPB SMCO4 TET2 TFE3 TFEB ZMAT2
Entrez ID		23566	22797
HPRD ID		05486	05294
Ensembl ID		ENSG00000171517	ENSG00000105967
Uniprot IDs		Q9UBY5	O14948
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Negative Regulation Of Peptide Secretion Negative Regulation Of Secretion Ascorbate Homeostasis Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules B Cell Receptor Complex Transmembrane Monodehydroascorbate Reductase Activity Negative Regulation Of Protein Secretion Negative Regulation Of Secretion By Cell	Deoxyguanosine Kinase Activity Deoxynucleoside Kinase Activity Deoxyadenosine Kinase Activity Deoxycytidine Kinase Activity DAMP Salvage Telomeric Repeat-containing RNA Binding DNA Binding Protein Dimerization Activity Melanocyte Apoptotic Process Lysosomal Membrane Regulation Of Osteoclast Differentiation Lysosome Organization Humoral Immune Response Defense Response To Gram-negative Bacterium DNA 5-methylcytosine Dioxygenase Activity Soluble NSF Attachment Protein Activity SNARE Complex Disassembly Cytidine Kinase Activity CMP Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Lysophosphatidic Acid Receptor Activity Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Regulation Of Myeloid Leukocyte Differentiation Cellular Response To Sodium Arsenite Lysosome
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?