TTC14 and SF3B2

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		TTC14	SF3B2
Gene Name		tetratricopeptide repeat domain 14	splicing factor 3b, subunit 2, 145kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding	Protein Binding Poly(A) RNA Binding
	Biological Process		MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Viral Process
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		11 interactors: CCDC85B CHERP DGCR14 FRA10AC1 IK NKAP RBM39 SF3B2 SNIP1 SNW1 SRRM2	25 interactors: APBB1 APP C7orf25 C8orf33 CSNK2A1 ERG FRA10AC1 HNRNPC KDM1A KIAA0368 LSM2 LSM3 PCBP2 PRPF40A RBM7 RBM8A SF3B4 SMAD3 SNRNP200 TCERG1 THOC1 TOE1 TTC14 U2AF1 ZCCHC10
Entrez ID		151613	10992
HPRD ID		15579	10410
Ensembl ID		ENSG00000163728	ENSG00000087365
Uniprot IDs		Q69YS0 Q86TA5 Q96N46	Q13435
PDB IDs			2DO5
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Metabolic Process RNA Splicing Gene Expression MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Vitamin D Receptor Signaling Pathway Negative Regulation Of Gene Expression Notch Signaling Pathway Regulation Of Vitamin D Receptor Signaling Pathway Cellular Metabolic Process Positive Regulation Of NFAT Protein Import Into Nucleus Positive Regulation By Host Of Viral Transcription	RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process MRNA Export From Nucleus Transcription, DNA-templated RNA Export From Nucleus RNA Biosynthetic Process MRNA 3'-end Processing Regulation Of Cell Cycle RNA 3'-end Processing Nuclear Export MRNA Transport Regulation Of Response To DNA Damage Stimulus Osteoblast Differentiation RNA Transport Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Cycle RNA Catabolic Process Posttranscriptional Regulation Of Gene Expression Cellular Macromolecule Catabolic Process Metabolic Process Termination Of RNA Polymerase II Transcription Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process Negative Regulation Of Protein Metabolic Process Apoptotic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Negative Regulation Of Potassium Ion Export Negative Regulation Of Isotype Switching To IgA Isotypes
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