TTC14 and DGCR14

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		TTC14	DGCR14
Gene Name		tetratricopeptide repeat domain 14	DiGeorge syndrome critical region gene 14
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding	Molecular_function Protein Binding
	Biological Process		MRNA Splicing, Via Spliceosome Nervous System Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CCDC85B CHERP DGCR14 FRA10AC1 IK NKAP RBM39 SF3B2 SNIP1 SNW1 SRRM2	11 interactors: CDK5RAP3 CRP DHX16 FRA10AC1 GNB2L1 LYST PFDN1 RBM4 TTC14 VIM WNK2
Entrez ID		151613	8220
HPRD ID		15579	03452
Ensembl ID		ENSG00000163728	ENSG00000100056
Uniprot IDs		Q69YS0 Q86TA5 Q96N46	Q96DF8
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Metabolic Process RNA Splicing Gene Expression MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Vitamin D Receptor Signaling Pathway Negative Regulation Of Gene Expression Notch Signaling Pathway Regulation Of Vitamin D Receptor Signaling Pathway Cellular Metabolic Process Positive Regulation Of NFAT Protein Import Into Nucleus Positive Regulation By Host Of Viral Transcription	Negative Regulation Of Translation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of CAMP Catabolic Process Mast Cell Secretory Granule Organization Regulation Of Neuron Differentiation Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Ion Homeostasis Regulation Of Cell Differentiation IRES-dependent Translational Initiation Cap-independent Translational Initiation Regulation Of Neurogenesis Endosome Transport Via Multivesicular Body Sorting Pathway Circadian Regulation Of Translation Defense Response To Bacterium Negative Regulation Of Oxidative Stress-induced Neuron Death Bergmann Glial Cell Differentiation Negative Regulation Of Vasodilation Secretion Of Lysosomal Enzymes Protein Ufmylation Negative Regulation Of Translation In Response To Stress Regulation Of Cell Development Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Protein Homooligomerization Positive Regulation Of Gastrulation Phospholipid Homeostasis Regulation Of Gene Expression Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Cytoplasmic Translational Initiation Negative Regulation Of Hydrogen Peroxide-induced Cell Death Positive Regulation Of Mitochondrial Depolarization Opsonization Leukocyte Mediated Immunity Adaptive Immune Response Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Phagocytosis Regulation Of Translation Cell Differentiation Central Nervous System Development Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Superoxide Anion Generation Regulation Of Interleukin-8 Secretion Regulation Of Cellular Localization Rhythmic Process Regulation Of Metabolic Process Cytoplasmic Translation Positive Regulation Of Sodium Ion Transmembrane Transport Regulation Of Translation In Response To Stress Negative Regulation Of Macrophage Derived Foam Cell Differentiation
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