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SF3B2 and MIR222
Number of citations of the paper that reports this interaction (PubMedID
28431233
)
0
Data Source:
BioGRID
(unspecified method)
SF3B2
MIR222
Description
splicing factor 3b subunit 2
microRNA 222
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
U2-type Spliceosomal Complex
U2 SnRNP
U12-type Spliceosomal Complex
Nuclear Speck
U2-type Precatalytic Spliceosome
Precatalytic Spliceosome
Catalytic Step 2 Spliceosome
Extracellular Space
RISC Complex
Extracellular Vesicle
Molecular Function
RNA Binding
Protein Binding
MRNA Base-pairing Post-transcriptional Repressor Activity
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
U2-type Prespliceosome Assembly
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Angiogenesis
Negative Regulation Of Interleukin-21 Production
MiRNA-mediated Post-transcriptional Gene Silencing
Negative Regulation Of Apoptotic Process
Host-mediated Suppression Of Viral Genome Replication
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Axon Regeneration
Negative Regulation Of Inflammatory Response
Positive Regulation Of Cardiac Muscle Cell Proliferation
Negative Regulation Of Cell Adhesion Molecule Production
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Schwann Cell Migration
Negative Regulation Of Hematopoietic Stem Cell Proliferation
Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Positive Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Negative Regulation Of Cardiac Muscle Cell Differentiation
Pathways
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS
Acne (severe) (
24927181
)
Bipolar disorder (
21926972
31043756
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Metabolite levels (
23823483
)
Interacting Genes
106 interacting genes:
AKAP9
APBB1
APP
C7orf25
C8orf33
CASK
CSNK2A1
ECPAS
ERG
FMR1
FRA10AC1
FXR1
FXR2
HNRNPC
KDM1A
LSM2
LSM3
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PCBP2
PRC1
PRKN
PRPF40A
RBM10
RBM11
RBM7
RBM8A
RNF10
SF3B4
SMAD3
SUMO2
TCERG1
THOC1
TOE1
TTC14
U2AF1
USP7
WBP4
ZCCHC10
75 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LIN28A
LRPPRC
MATR3
MSI2
NONO
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
QARS1
RBFOX2
RBM14
RBM4
RBMS2
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
SUGP2
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
10992
407007
HPRD ID
10410
Ensembl ID
ENSG00000087365
ENSG00000207725
Uniprot IDs
Q13435
PDB IDs
2DO5
5Z56
5Z57
5Z58
6AH0
6AHD
6FF4
6FF7
6QX9
6Y50
6Y53
6Y5Q
7ABG
7ABH
7ABI
7DVQ
7EVO
7ONB
7Q3L
7Q4O
7Q4P
7QTT
7VPX
8CH6
8H6E
8H6J
8H6K
8H6L
8HK1
8I0P
8I0R
8I0S
8I0T
8I0U
8I0V
8QO9
8QXD
8QZS
8R08
8R09
8R0A
8R0B
8RM5
8Y7E
Enriched GO Terms of Interacting Partners
?
MiRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Extracellular Vesicle
Negative Regulation Of Translation
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
MRNA Destabilization
RNA Destabilization
Positive Regulation Of MRNA Catabolic Process
Regulation Of Translation
Regulation Of Macromolecule Metabolic Process
Regulation Of MRNA Stability
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of RNA Stability
Positive Regulation Of MRNA Metabolic Process
Regulation Of Angiogenesis
Regulation Of MRNA Metabolic Process
Regulation Of Vasculature Development
Negative Regulation Of Cytokine Production
Regulation Of Metabolic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Cell Motility
Negative Regulation Of Locomotion
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Multicellular Organismal Process
Regulation Of Endothelial Cell Migration
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Developmental Process
Negative Regulation Of Endothelial Cell Migration
Negative Regulation Of Signal Transduction
Positive Regulation Of Catabolic Process
Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
RNA Binding
Nucleic Acid Binding
RNA Processing
RNA Splicing
RNA Metabolic Process
MRNA Processing
MRNA Metabolic Process
Nucleic Acid Metabolic Process
Nucleobase-containing Compound Metabolic Process
MRNA Binding
Regulation Of RNA Splicing
Regulation Of MRNA Metabolic Process
Nucleus
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Macromolecule Metabolic Process
Ribonucleoprotein Complex
Post-transcriptional Regulation Of Gene Expression
Spliceosomal Complex
Catalytic Step 2 Spliceosome
Nucleoplasm
Negative Regulation Of MRNA Metabolic Process
Regulation Of MRNA Processing
Regulation Of Translation
Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Catabolic Process
MRNA 3'-UTR Binding
MiRNA Binding
Regulation Of Gene Expression
Cytoplasmic Stress Granule
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Translation
Negative Regulation Of MRNA Catabolic Process
RNA Stabilization
Positive Regulation Of Gene Expression
Regulation Of Primary Metabolic Process
MRNA Stabilization
Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Cytoplasmic Translation
Negative Regulation Of Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Aminoacyl-tRNA Synthetase Multienzyme Complex
CRD-mediated MRNA Stabilization
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA 5'-UTR Binding
Regulation Of MRNA Stability
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Translation
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Tagcloud (Intersection)
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