SF3B2 and MIR9-2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		SF3B2	MIR9-2
Description		splicing factor 3b subunit 2	microRNA 9-2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome	RISC Complex
	Molecular Function	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing U2-type Prespliceosome Assembly	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Metabolite levels ( 23823483)	Body mass index ( 26426971) Regular attendance at a religious group ( 29970889)
Interacting Genes		106 interacting genes: AKAP9 APBB1 APP C7orf25 C8orf33 CASK CSNK2A1 ECPAS ERG FMR1 FRA10AC1 FXR1 FXR2 HNRNPC KDM1A LSM2 LSM3 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP2 PRC1 PRKN PRPF40A RBM10 RBM11 RBM7 RBM8A RNF10 SF3B4 SMAD3 SUMO2 TCERG1 THOC1 TOE1 TTC14 U2AF1 USP7 WBP4 ZCCHC10	76 interacting genes: ADARB1 APOBEC3B C1QBP CELF1 CELF2 CPSF7 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 FAM98A FUS GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM4B RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SFPQ SYNCRIP TAF15 TENT2 TIAL1 TRA2A TRA2B UTP20 YBX1 YBX3 ZC3H11A ZFR ZNF346 ZNF385A
Entrez ID		10992	407047
HPRD ID		10410
Ensembl ID		ENSG00000087365	ENSG00000284447
Uniprot IDs		Q13435
PDB IDs		2DO5 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6QX9 6Y50 6Y53 6Y5Q 7ABG 7ABH 7ABI 7DVQ 7EVO 7ONB 7Q3L 7Q4O 7Q4P 7QTT 7VPX 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y7E
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Stability Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of RNA Stability Positive Regulation Of MRNA Metabolic Process Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Regulation Of Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Developmental Process Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Signal Transduction Positive Regulation Of Catabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Signaling Negative Regulation Of Cell Communication	RNA Binding Nucleic Acid Binding RNA Processing MRNA Processing RNA Metabolic Process RNA Splicing MRNA Binding MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex Nucleus MRNA 3'-UTR Binding Nucleoplasm Regulation Of Translation MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process Spliceosomal Complex Regulation Of Gene Expression Negative Regulation Of Translation Catalytic Step 2 Spliceosome Regulation Of Macromolecule Biosynthetic Process Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Macromolecule Metabolic Process MiRNA Binding Nucleolus Regulation Of RNA Metabolic Process MRNA Stabilization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Protein Metabolic Process Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation
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