SF3B2 and C7orf25

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		SF3B2	C7orf25
Description		splicing factor 3b subunit 2	chromosome 7 open reading frame 25
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing U2-type Prespliceosome Assembly
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Metabolite levels ( 23823483)	Asthma ( 29273806) Ceramide levels (C24:0) ( 32489964)
Interacting Genes		106 interacting genes: AKAP9 APBB1 APP C7orf25 C8orf33 CASK CSNK2A1 ECPAS ERG FMR1 FRA10AC1 FXR1 FXR2 HNRNPC KDM1A LSM2 LSM3 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP2 PRC1 PRKN PRPF40A RBM10 RBM11 RBM7 RBM8A RNF10 SF3B4 SMAD3 SUMO2 TCERG1 THOC1 TOE1 TTC14 U2AF1 USP7 WBP4 ZCCHC10	20 interacting genes: BRD4 CEP70 CRYM DACT1 EZH2 FRA10AC1 FYN FZR1 GTPBP1 HAP1 HEXD MTOR MX1 NGEF PTN RASSF1 RPL36AL SF3B2 TARS1 UBE2D1
Entrez ID		10992	79020
HPRD ID		10410	09861
Ensembl ID		ENSG00000087365	ENSG00000136197
Uniprot IDs		Q13435	Q9BPX7
PDB IDs		2DO5 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6QX9 6Y50 6Y53 6Y5Q 7ABG 7ABH 7ABI 7DVQ 7EVO 7ONB 7Q3L 7Q4O 7Q4P 7QTT 7VPX 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y7E
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Stability Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of RNA Stability Positive Regulation Of MRNA Metabolic Process Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Regulation Of Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Developmental Process Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Signal Transduction Positive Regulation Of Catabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Signaling Negative Regulation Of Cell Communication	Regulation Of Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of Intracellular Signal Transduction Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Projection Organization Regulation Of Protein Metabolic Process Positive Regulation Of Dendrite Development Regulation Of Cell Projection Organization Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Metabolic Process Regulation Of Gliogenesis Positive Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Protein Ubiquitination Cytoplasmic Translation Ephrin Receptor Binding Positive Regulation Of Post-translational Protein Modification Delta1-piperideine-2-carboxylate Reductase Activity Nucleus Thiomorpholine-carboxylate Dehydrogenase Activity Regulation Of Cellular Component Organization Positive Regulation Of Neuron Projection Development Positive Regulation Of Protein Modification Process Hepatocyte Homeostasis Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Modification Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Neurogenesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Translation Transmembrane Transporter Binding Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Glial Cell Differentiation Regulation Of Protein Catabolic Process Pyrimidine-containing Compound Biosynthetic Process Regulation Of Oligodendrocyte Differentiation Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Cellular Response To Glycine Response To Singlet Oxygen Positive Regulation Of Neurotrophin Production Histone H4K8ac Reader Activity Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Myelination T Cell Costimulation Regulation Of Cell Cycle Process Regulation Of Neuron Projection Development Cellular Response To Stress Regulation Of Nervous System Development Positive Regulation Of Cell Development Dendrite Morphogenesis Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
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