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CTSG and SELPLG
Number of citations of the paper that reports this interaction (PubMedID
11520793
)
0
Data Source:
HPRD
(in vivo)
CTSG
SELPLG
Description
cathepsin G
selectin P ligand
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Lysosome
Cytosol
Plasma Membrane
Cytoplasmic Stress Granule
Membrane
Secretory Granule
Extracellular Matrix
Azurophil Granule Lumen
Extracellular Exosome
Uropod
Plasma Membrane
Membrane
Plasma Membrane Raft
Molecular Function
Serine-type Endopeptidase Activity
Protein Binding
Heparin Binding
Peptidase Activity
Serine-type Peptidase Activity
Hydrolase Activity
Receptor Ligand Activity
Caspase Binding
Virus Receptor Activity
Signaling Receptor Binding
Protein Binding
Biological Process
Angiotensin Maturation
Monocyte Chemotaxis
Protein Phosphorylation
Proteolysis
Chemotaxis
Immune Response
Protein Processing
Cytokine-mediated Signaling Pathway
Antibacterial Humoral Response
Extracellular Matrix Disassembly
Platelet Activation
Response To Lipopolysaccharide
Purinergic Nucleotide Receptor Signaling Pathway
Neutrophil Activation
Defense Response To Bacterium
Positive Regulation Of Immune Response
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Defense Response To Fungus
Negative Regulation Of T Cell Activation
Protein Maturation
Neutrophil-mediated Killing Of Gram-positive Bacterium
Cellular Response To Lipopolysaccharide
Biofilm Matrix Disassembly
Positive Regulation Of Platelet Aggregation
Cell Adhesion
Symbiont Entry Into Host Cell
Leukocyte Migration
Leukocyte Tethering Or Rolling
Leukocyte Adhesive Activation
Cellular Response To Interleukin-6
Pathways
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Interleukin-1 processing
Neutrophil degranulation
Antimicrobial peptides
Suppression of apoptosis
Purinergic signaling in leishmaniasis infection
Cell surface interactions at the vascular wall
Drugs
Bis-Napthyl Beta-Ketophosphonic Acid
2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid
Neihulizumab
Diseases
GWAS
Congenital heart disease (maternal effect) (
28468790
)
Conotruncal heart defects (maternal effects) (
28468790
)
Acne (severe) (
24927181
)
Blood protein levels (
30072576
)
Brain morphology (MOSTest) (
32665545
)
Conduct disorder (symptom count) (
20585324
)
Interacting Genes
30 interacting genes:
AGT
C3
CAMP
CASP7
CXCL12
CXCR4
CYSRT1
ERBIN
F2R
F2RL1
F2RL2
F5
GP1BA
IGFBP3
KNG1
KRT31
LRP1
NOTCH2NLA
PARP1
PICK1
PPBP
SDC1
SELPLG
SERPINA1
SERPINA3
SERPINB13
SERPINB4
SERPIND1
THBS1
VCAM1
14 interacting genes:
BACE1
CTSG
GALNT4
MAGEA1
MSN
SELE
SELL
SELP
SLC13A1
SYK
TNIP1
TPST1
TPST2
VCAN
Entrez ID
1511
6404
HPRD ID
00289
02845
Ensembl ID
ENSG00000100448
ENSG00000110876
Uniprot IDs
P08311
Q14242
PDB IDs
1AU8
1CGH
1KYN
1T32
6VTM
7H6G
7H6H
8D4S
8D4V
8D7I
8D7K
8G24
8G25
8G26
9ASX
9ATK
1G1S
Enriched GO Terms of Interacting Partners
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Coagulation
Blood Coagulation
Hemostasis
Thrombin-activated Receptor Activity
Extracellular Space
Inflammatory Response
Regulation Of Body Fluid Levels
Extracellular Region
Platelet Alpha Granule Lumen
Thrombin-activated Receptor Signaling Pathway
Serine-type Endopeptidase Inhibitor Activity
Endopeptidase Inhibitor Activity
Defense Response
Peptidase Inhibitor Activity
Circulatory System Process
Extracellular Exosome
Regulation Of Blood Coagulation
Regulation Of Hemostasis
Regulation Of Biological Quality
Positive Regulation Of Programmed Cell Death
Signaling Receptor Binding
Regulation Of Secretion By Cell
Chronic Inflammatory Response
Endoplasmic Reticulum Lumen
Regulation Of Secretion
Response To External Biotic Stimulus
Protease Binding
Cell Activation
Positive Regulation Of Multicellular Organismal Process
Killing Of Cells Of Another Organism
Leukocyte Migration
Proteinase-activated Receptor Activity
Response To Cytokine
Regulation Of Wound Healing
Regulation Of Programmed Cell Death
Response To Peptide
Platelet Alpha Granule
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure
G Protein-coupled Receptor Signaling Pathway
Vascular Process In Circulatory System
Positive Regulation Of Cytosolic Calcium Ion Concentration
Blood Vessel Diameter Maintenance
Regulation Of Tube Size
Cellular Response To Cytokine Stimulus
Immune System Process
Regulation Of Renin Secretion Into Blood Stream
Regulation Of Transport
Positive Regulation Of Transport
Leukocyte Cell-cell Adhesion
Leukocyte Migration
Oligosaccharide Binding
Carbohydrate Binding
Leukocyte Tethering Or Rolling
Sialic Acid Binding
Protein-tyrosine Sulfotransferase Activity
Leukocyte Adhesion To Vascular Endothelial Cell
Cell-cell Adhesion
Cell Adhesion
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Cell Migration
Glycosphingolipid Binding
Regulation Of Platelet Activation
Cell Motility
Positive Regulation Of Leukocyte Tethering Or Rolling
Regulation Of Leukocyte Tethering Or Rolling
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Golgi Lumen
Response To Lipopolysaccharide
Immune System Process
Phospholipase Binding
Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Response To Molecule Of Bacterial Origin
Positive Regulation Of Cell-cell Adhesion
Positive Regulation Of Immune System Process
Neutrophil Activation
Positive Regulation Of Receptor Internalization
Regulation Of Platelet Aggregation
Regulation Of Leukocyte Cell-cell Adhesion
Heparin Binding
Regulation Of Immune System Process
Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Regulation Of Cellular Extravasation
Pattern Recognition Receptor Signaling Pathway
Regulation Of Inflammatory Response
Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Innate Immune Response-activating Signaling Pathway
Trans-Golgi Network
Signaling Receptor Ligand Precursor Processing
Response To Lipid
Biofilm Matrix Disassembly
Regulation Of Defense Response
Mevalonate Kinase Activity
Interleukin-15 Receptor Binding
Positive Regulation Of Interleukin-3 Production
Peptidyl-tyrosine Sulfation
Golgi-associated Vesicle Lumen
Activation Of Innate Immune Response
Response To External Biotic Stimulus
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Tagcloud (Intersection)
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