SELPLG and GALNT4

Number of citations of the paper that reports this interaction (PMID 9804815)
26

Data Source:
HPRD (in vitro)

		SELPLG	GALNT4
Gene Name		selectin P ligand	polypeptide N-acetylgalactosaminyltransferase 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Receptor Binding Protein Binding	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Cell Adhesion Blood Coagulation Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6	Carbohydrate Metabolic Process Protein O-linked Glycosylation O-glycan Processing Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Cell surface interactions at the vascular wall	Post-translational protein modification O-linked glycosylation of mucins O-linked glycosylation
Drugs
Diseases
GWAS		Conduct disorder (symptom count) ( 20585324)
Protein-Protein Interactions		13 interactors: BACE1 CTSG GALNT4 MAGEA1 MSN SELE SELL SELP SYK TNIP1 TPST1 TPST2 VCAN	2 interactors: MUC1 SELPLG
Entrez ID		6404	8693
HPRD ID		02845	09152
Ensembl ID		ENSG00000110876	ENSG00000257594
Uniprot IDs		Q14242	Q8N4A0
PDB IDs		1G1S
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Peptidyl-tyrosine Sulfation Leukocyte Cell-cell Adhesion Cell Adhesion Regulation Of Immune System Process Inflammatory Response Cell Migration Protein Sulfation Cell Motility Single Organismal Cell-cell Adhesion Leukocyte Tethering Or Rolling Sulfation Locomotion Regulation Of Leukocyte Migration Defense Response Immune System Process Blood Coagulation Hemostasis Movement Of Cell Or Subcellular Component Positive Regulation Of Immune System Process Response To Bacterium Cellular Extravasation Regulation Of Platelet Activation Defense Response To Bacterium Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Regulation Of Body Fluid Levels Response To Fungus Wound Healing Response To Wounding Response To Other Organism Response To Biotic Stimulus Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Lipopolysaccharide Platelet Degranulation Response To Molecule Of Bacterial Origin Sulfur Compound Metabolic Process Regulation Of Immune Response Response To Stress Positive Regulation Of Leukocyte Migration Glycoprotein Biosynthetic Process Cellular Response To Molecule Of Fungal Origin Neutrophil Mediated Killing Of Gram-positive Bacterium Beta Selection Selenium Compound Metabolic Process Positive Regulation Of Interleukin-3 Biosynthetic Process Regulation Of Blood Coagulation Glycoprotein Metabolic Process Serotonin Secretion By Platelet Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process Prevention Of Polyspermy	Leukocyte Adhesive Activation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Transcription By Competitive Promoter Binding DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Leukocyte Tethering Or Rolling Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Histone H4 Acetylation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Histone Acetylation Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Protein Acetylation Cellular Response To Interleukin-6 Cellular Extravasation Response To Interleukin-6 Regulation Of Signal Transduction By P53 Class Mediator O-glycan Processing Regulation Of Histone Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Histone Modification Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Protein O-linked Glycosylation Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Cycle Arrest Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Regulation Of Response To DNA Damage Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Mitotic Cell Cycle Phase Transition DNA Damage Checkpoint Regulation Of Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Checkpoint
Tagcloud ?		aggregates allele angioplasty atherothrombosis carrier carriers depended glycoprotein ile62 inducible irrespective leukocyte lpa monocyte mpa npa pivotal platelet pp pro715 psgl selectin sp stenting stronger thrombin trap variations
Tagcloud (Difference) ?		aggregates allele angioplasty atherothrombosis carrier carriers depended glycoprotein ile62 inducible irrespective leukocyte lpa monocyte mpa npa pivotal platelet pp pro715 psgl selectin sp stenting stronger thrombin trap variations
Tagcloud (Intersection) ?