SELPLG and TPST2

Number of citations of the paper that reports this interaction (PMID 17558413)
13

Data Source:
HPRD (in vitro)

		SELPLG	TPST2
Gene Name		selectin P ligand	tyrosylprotein sulfotransferase 2
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane	Golgi Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Binding Protein Binding	Protein-tyrosine Sulfotransferase Activity
	Biological Process	Cell Adhesion Blood Coagulation Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6	Peptidyl-tyrosine Sulfation Fusion Of Sperm To Egg Plasma Membrane Prevention Of Polyspermy
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Conduct disorder (symptom count) ( 20585324)
Protein-Protein Interactions		13 interactors: BACE1 CTSG GALNT4 MAGEA1 MSN SELE SELL SELP SYK TNIP1 TPST1 TPST2 VCAN	5 interactors: CCR1 CCR8 CMKLR1 GPR1 SELPLG
Entrez ID		6404	8459
HPRD ID		02845	07217
Ensembl ID		ENSG00000110876	ENSG00000128294
Uniprot IDs		Q14242	O60704
PDB IDs		1G1S	3AP1 3AP2 3AP3
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Peptidyl-tyrosine Sulfation Leukocyte Cell-cell Adhesion Cell Adhesion Regulation Of Immune System Process Inflammatory Response Cell Migration Protein Sulfation Cell Motility Single Organismal Cell-cell Adhesion Leukocyte Tethering Or Rolling Sulfation Locomotion Regulation Of Leukocyte Migration Defense Response Immune System Process Blood Coagulation Hemostasis Movement Of Cell Or Subcellular Component Positive Regulation Of Immune System Process Response To Bacterium Cellular Extravasation Regulation Of Platelet Activation Defense Response To Bacterium Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Regulation Of Body Fluid Levels Response To Fungus Wound Healing Response To Wounding Response To Other Organism Response To Biotic Stimulus Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Lipopolysaccharide Platelet Degranulation Response To Molecule Of Bacterial Origin Sulfur Compound Metabolic Process Regulation Of Immune Response Response To Stress Positive Regulation Of Leukocyte Migration Glycoprotein Biosynthetic Process Cellular Response To Molecule Of Fungal Origin Neutrophil Mediated Killing Of Gram-positive Bacterium Beta Selection Selenium Compound Metabolic Process Positive Regulation Of Interleukin-3 Biosynthetic Process Regulation Of Blood Coagulation Glycoprotein Metabolic Process Serotonin Secretion By Platelet Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process Prevention Of Polyspermy	Chemokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine G-protein Coupled Receptor Signaling Pathway Locomotion Cytokine-mediated Signaling Pathway Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Leukocyte Migration Chemotaxis Cellular Response To Organic Substance Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Behavior Immune System Process Regulation Of Chemotaxis G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Leukocyte Adhesive Activation Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Response To Organic Substance Regulation Of Behavior Leukocyte Migration Cell Adhesion Cell Surface Receptor Signaling Pathway Immune Response Cellular Calcium Ion Homeostasis Positive Regulation Of Macrophage Chemotaxis Calcium Ion Homeostasis Cellular Response To Stimulus Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Positive Regulation Of Monocyte Chemotaxis Leukocyte Tethering Or Rolling Cellular Metal Ion Homeostasis Regulation Of Macrophage Chemotaxis Regulation Of Monocyte Chemotaxis Dendritic Cell Chemotaxis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Response To External Stimulus Negative Regulation Of Interleukin-12 Production Negative Regulation Of Bone Mineralization Negative Regulation Of Biomineral Tissue Development Cellular Chemical Homeostasis Response To Stimulus Dendritic Cell Migration Ion Homeostasis
Tagcloud ?		aggregates allele angioplasty atherothrombosis carrier carriers depended glycoprotein ile62 inducible irrespective leukocyte lpa monocyte mpa npa pivotal platelet pp pro715 psgl selectin sp stenting stronger thrombin trap variations	ameliorates backcross catalyzes ch chr chrs congenic d2mit255 d2mit304 d2mit62 dw dwarfism genetical grt hypoplasia hyporesponsiveness hypothyroidism indispensable linkage organogenesis progenies qtl qtls sulfation sulfotransferase svjcl ter thyroid tyrosylprotein
Tagcloud (Difference) ?		aggregates allele angioplasty atherothrombosis carrier carriers depended glycoprotein ile62 inducible irrespective leukocyte lpa monocyte mpa npa pivotal platelet pp pro715 psgl selectin sp stenting stronger thrombin trap variations	ameliorates backcross catalyzes ch chr chrs congenic d2mit255 d2mit304 d2mit62 dw dwarfism genetical grt hypoplasia hyporesponsiveness hypothyroidism indispensable linkage organogenesis progenies qtl qtls sulfation sulfotransferase svjcl ter thyroid tyrosylprotein
Tagcloud (Intersection) ?