H3F3C and KAT6A

Number of citations of the paper that reports this interaction (PMID 17925393)
11

Data Source:
BioGRID (enzymatic study)

		H3F3C	KAT6A
Gene Name		H3 histone, family 3C	K(lysine) acetyltransferase 6A
Image
Gene Ontology Annotations	Cellular Component	Nucleosome Nuclear Euchromatin	Nucleosome Nucleus Nucleoplasm Nucleolus Golgi Apparatus PML Body MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Nucleosomal DNA Binding Protein Heterodimerization Activity	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Acetyltransferase Activity
	Biological Process	Positive Regulation Of Cell Growth	Heart Morphogenesis DNA Packaging Chromatin Organization Nucleosome Assembly Transcription, DNA-templated Protein Acetylation Histone Acetylation Myeloid Cell Differentiation Somatic Stem Cell Maintenance Embryonic Hemopoiesis Aorta Morphogenesis Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Histone H3 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Face Morphogenesis Cellular Senescence
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: KAT6A KDM1A KDM4B NASP PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1 WHSC1L1	18 interactors: AKT1 ATN1 ATXN1 CREBBP H3F3C HIST1H3A HIST1H4A HIST1H4I HIST2H3C HIST3H3 HIST4H4 MAFK PML RERE RUNX1 SPI1 TP53 UBE2U
Entrez ID		440093	7994
HPRD ID		18443	03244
Ensembl ID		ENSG00000188375	ENSG00000083168
Uniprot IDs		Q6NXT2	A5PKX7 Q92794
PDB IDs		3KV4	1M36 2LN0 2OZU 2RC4 3V43
Enriched GO Terms of Interacting Partners?		Chromatin Modification Chromatin Organization Chromosome Organization Histone Modification Histone Methylation Protein Methylation Methylation Organelle Organization Peptidyl-amino Acid Modification Histone Lysine Methylation Peptidyl-lysine Methylation Peptidyl-lysine Modification Histone H4-R3 Methylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation Cellular Protein Modification Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Peptidyl-lysine Dimethylation Protein Metabolic Process Nucleosome Assembly Regulation Of Metabolic Process Chromatin Assembly	DNA Methylation On Cytosine Chromatin Silencing At RDNA Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Chromatin Silencing Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication-dependent Nucleosome Assembly Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Chromosome Organization Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Methylation Negative Regulation Of Cellular Metabolic Process Histone H4-K20 Demethylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process DNA Modification Regulation Of RNA Metabolic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Megakaryocyte Differentiation Gene Silencing Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Chromatin Assembly Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Chromatin Assembly Or Disassembly Chromatin Modification Regulation Of Myeloid Cell Differentiation DNA Packaging Organelle Organization Histone Modification Telomere Maintenance DNA Metabolic Process Regulation Of Megakaryocyte Differentiation Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Cell Differentiation Regulation Of Cell Differentiation Nucleocytoplasmic Transport CENP-A Containing Nucleosome Assembly Nuclear Transport DNA Conformation Change Protein Import Into Nucleus
Tagcloud ?			acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 ncoa3 overlap progenitor progenitors proliferative tale tif2 translocations
Tagcloud (Difference) ?			acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 ncoa3 overlap progenitor progenitors proliferative tale tif2 translocations
Tagcloud (Intersection) ?