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H3-5 and PRMT7
Number of citations of the paper that reports this interaction (PubMedID
23455924
)
0
Data Source:
BioGRID
(two hybrid)
H3-5
PRMT7
Description
H3.5 histone
protein arginine methyltransferase 7
Image
No pdb structure
GO Annotations
Cellular Component
Nucleosome
Euchromatin
Nucleus
Nucleoplasm
Chromosome
Fibrillar Center
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
DNA Binding
Protein Binding
Structural Constituent Of Chromatin
Nucleosomal DNA Binding
Protein Heterodimerization Activity
Protein Binding
Methyltransferase Activity
S-adenosylmethionine-dependent Methyltransferase Activity
Protein-arginine N-methyltransferase Activity
Transferase Activity
Protein-arginine Omega-N Monomethyltransferase Activity
Protein-arginine Omega-N Symmetric Methyltransferase Activity
Histone Methyltransferase Activity
Histone Binding
Ribonucleoprotein Complex Binding
Histone H4R3 Methyltransferase Activity
Histone H4 Methyltransferase Activity
Biological Process
Positive Regulation Of Cell Growth
Spliceosomal SnRNP Assembly
Chromatin Organization
Chromatin Remodeling
Regulation Of DNA-templated Transcription
Peptidyl-arginine Methylation
Cell Differentiation
Methylation
Genomic Imprinting
Pathways
RMTs methylate histone arginines
Drugs
Diseases
GWAS
A body shape index (
34021172
)
Birth weight (
31043758
)
Body mass index (
25673413
28892062
)
Lipoprotein (a) levels (
33730874
)
Magnesium levels (
20700443
)
Offspring birth weight (
31043758
)
Refractive error (
32231278
)
Schizophrenia (
31579629
)
Serum metabolite levels (
23093944
)
Weight (
28552196
)
Interacting Genes
15 interacting genes:
DAXX
DNAJC9
FBLIM1
KAT6A
KDM1A
KDM4B
NASP
NSD3
PRMT5
PRMT6
PRMT7
SETMAR
SMYD1
SMYD3
SUV39H1
14 interacting genes:
CTCFL
DIO3
EIF2S1
H2AC20
H3-5
H3C1
H4C1
MNDA
NFKBID
POT1
SNRPB
UBC
ZBTB24
ZNF438
Entrez ID
440093
54496
HPRD ID
18443
15174
Ensembl ID
ENSG00000188375
ENSG00000132600
Uniprot IDs
Q6NXT2
A0A8I5KPP4
A0A8I5KXS9
A0A8I5KYD6
A0A8I5KZ05
A0A8I5KZ92
H3BNC0
Q9NVM4
PDB IDs
2PUY
3KV4
4Z5T
5BWN
5BWO
5F6K
5I3L
6OI3
7TRL
7W67
7W6I
7W6J
7W6L
7Y0I
7ZEZ
8Q1G
8Q1H
8Q1J
8RBX
8SR6
8T4F
8T4R
8ZXC
9C0O
9DZN
Enriched GO Terms of Interacting Partners
?
Chromatin Remodeling
Chromatin Organization
Histone Methyltransferase Activity
Methyltransferase Activity
Methylation
Histone H3 Methyltransferase Activity
Histone H4R3 Methyltransferase Activity
Nucleosome Assembly
Protein-arginine N-methyltransferase Activity
Nucleosome Organization
Histone Binding
Histone H3K4 Methyltransferase Activity
Protein-DNA Complex Assembly
Histone Arginine N-methyltransferase Activity
Protein-arginine Omega-N Symmetric Methyltransferase Activity
Transferase Activity
Regulation Of Signal Transduction By P53 Class Mediator
Histone H3K36 Dimethyltransferase Activity
Nucleoplasm
Peptidyl-arginine Methylation
Protein-arginine Omega-N Monomethyltransferase Activity
Nucleus
Chromosome
Histone H4 Methyltransferase Activity
Transcription Corepressor Activity
Histone H3K4 Trimethyltransferase Activity
Regulation Of Nucleobase-containing Compound Metabolic Process
P53 Binding
Histone H3K36 Methyltransferase Activity
Histone H3K9 Demethylase Activity
Protein-containing Complex Assembly
Regulation Of DNA-templated Transcription
Negative Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Epigenetic Regulation Of Gene Expression
Negative Regulation Of RNA Metabolic Process
Protein-containing Complex Organization
Regulation Of RNA Metabolic Process
Positive Regulation Of ATP-dependent Activity
Histone Demethylase Activity
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Metabolic Process
Chromatin
Nuclear Androgen Receptor Binding
Histone Methyltransferase Complex
S-adenosylmethionine-dependent Methyltransferase Activity
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of ATP-dependent Activity
Structural Constituent Of Chromatin
Nucleosome
DNA Binding
Chromosome
Nucleus
Protein Heterodimerization Activity
Telomere Organization
Translation Initiation Ternary Complex
Positive Regulation Of DNA Strand Elongation
Positive Regulation Of Telomeric D-loop Disassembly
G-rich Single-stranded DNA Binding
Retinal Cone Cell Apoptotic Process
Thyroxine 5'-deiodinase Activity
Thyroxine 5-deiodinase Activity
Thyroid Hormone Catabolic Process
Brown Fat Cell Proliferation
Response To Manganese-induced Endoplasmic Reticulum Stress
Glial Limiting End-foot
Nucleoplasm
SnRNP Binding
U2 SnRNP Binding
Chromatin Remodeling
Epigenetic Regulation Of Gene Expression
Positive Regulation Of Telomeric Loop Disassembly
8-hydroxy-2'-deoxyguanosine DNA Binding
Telomeric G-quadruplex DNA Binding
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Tagcloud (Difference)
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Tagcloud (Intersection)
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