CTF1 and MAGEA6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		CTF1	MAGEA6
Description		cardiotrophin 1	MAGE family member A6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus
	Molecular Function	Cytokine Activity Leukemia Inhibitory Factor Receptor Binding Protein Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Via JAK-STAT Cell-cell Signaling Nervous System Development Muscle Organ Development Positive Regulation Of Cell Population Proliferation Neuron Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Neuron Development	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy
Pathways		IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS		Red blood cell count ( 27863252) Triglyceride levels ( 28334899) Triglycerides ( 20686565 24097068)	Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		9 interacting genes: APP EP300 IL6ST LIFR MAGEA6 S100A1 S100A6 S100P TLX1	75 interacting genes: ACOT7 ACTN3 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATOSA ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D PRKAA1 RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76
Entrez ID		1489	4105
HPRD ID		02699	02168
Ensembl ID		ENSG00000150281	ENSG00000197172
Uniprot IDs		Q16619	P43360
PDB IDs
Enriched GO Terms of Interacting Partners?		Leukemia Inhibitory Factor Receptor Activity Ciliary Neurotrophic Factor Receptor Activity Leukemia Inhibitory Factor Signaling Pathway Oncostatin-M Receptor Activity Oncostatin-M-mediated Signaling Pathway Ciliary Neurotrophic Factor-mediated Signaling Pathway Ciliary Neurotrophic Factor Receptor Binding Calcium-dependent Protein Binding T-helper 17 Cell Lineage Commitment S100 Protein Binding T-helper Cell Lineage Commitment Transition Metal Ion Binding CD4-positive, Alpha-beta T Cell Lineage Commitment Alpha-beta T Cell Lineage Commitment CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Receptor Complex T Cell Lineage Commitment Extracellular Region Cytokine Binding Growth Factor Binding Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Myeloid Cell Development Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Homodimerization Activity Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Cell Surface Receptor Signaling Pathway Via JAK-STAT Histone Crotonyltransferase Activity Cytokine Receptor Activity External Side Of Plasma Membrane Regulation Of ATP Metabolic Process Acetylcholine Receptor Activator Activity Positive Regulation Of Cell Activation Cell Body Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Purine Nucleotide Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Identical Protein Binding	Protein Binding SNARE Complex Suppression Of Viral Release By Host
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