CTAG1B and TRIB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTAG1B	TRIB3
Description		cancer/testis antigen 1B	tribbles pseudokinase 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Transcription Corepressor Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Kinase Activity Enzyme Binding Protein Kinase Binding Protein Serine/threonine Kinase Inhibitor Activity Mitogen-activated Protein Kinase Kinase Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Regulator Activity Ubiquitin Ligase Activator Activity
	Biological Process	TRNA Threonylcarbamoyladenosine Metabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Regulation Of Autophagy Regulation Of D-glucose Transmembrane Transport Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Insulin Stimulus Response To Endoplasmic Reticulum Stress Regulation Of MAP Kinase Activity Negative Regulation Of MAPK Cascade Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Insulin Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways			PIP3 activates AKT signaling Activation of AKT2 PPARA activates gene expression Negative regulation of the PI3K/AKT network CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS			Information processing speed ( 21130836) Logical memory (delayed recall) ( 29274321) Logical memory (immediate recall) ( 29274321)
Interacting Genes		81 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1A CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MAGEC1 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX	100 interacting genes: ACACA AKAP8L AKT1 AKT2 APOBEC3A APOBEC3C APP ARMC7 ATF4 BAG3 BCL6 BFSP2 BMPR2 C21orf58 C22orf39 CBX8 CHAF1A CLCNKA COPS6 CTAG1A CTAG1B DDIT3 DPPA3 DTX2 EEF1G EFEMP2 EPHB6 EXOSC5 FAAP20 FAM161A FAM90A1 FBXO7 GDF9 GIT1 GLIS3 GPATCH2L GRB2 HAT1 HDAC4 HLA-B HNRNPF HOXB5 HOXC8 IL16 INCA1 INO80B IRX6 KANK2 KAT5 KLHL38 KRT26 LENG1 LMO2 LMO3 MDFI MDM2 MISP MYC OIP5 OSTF1 PADI4 PARD6B PCSK5 PITX2 PKNOX2 PML PPP1R26 PRKAB2 PRMT5 PRR19 PSMA3 RBM4 RBM48 RELA RIDA RPGRIP1 RPSA SAMD11 SAXO1 SAXO4 SCNM1 SETDB1 SHFL SNRPC SPAG8 SPG21 SUOX TCF19 TEKT3 TEKT4 TLE5 TRIM55 TRIM63 TTC23 TWIST1 UBTD2 USP20 UTP23 ZNF417 ZNF587
Entrez ID		1485	57761
HPRD ID		02151	09836
Ensembl ID		ENSG00000184033	ENSG00000101255
Uniprot IDs		P78358	B4DMM9 J3KR25 Q96RU7
PDB IDs		1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1
Enriched GO Terms of Interacting Partners?		Protein Binding Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Positive Regulation Of ERAD Pathway Antigen Processing And Presentation Of Exogenous Antigen Regulation Of ERAD Pathway MHC Class II Protein Complex Binding ER To Golgi Transport Vesicle Membrane Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Peptide Antigen Binding TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Myeloid Dendritic Cell Antigen Processing And Presentation Transport Vesicle Membrane Antigen Processing And Presentation Trans-Golgi Network Membrane Skeletal Muscle Atrophy Dendritic Cell Antigen Processing And Presentation Positive Regulation Of Proteasomal Protein Catabolic Process Clathrin-coated Endocytic Vesicle Membrane Protein Targeting To ER Regulation Of Protein Ubiquitination Skeletal Muscle Adaptation Striated Muscle Atrophy Lysosomal Membrane Endocytic Vesicle Membrane Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Autolysosome Membrane Muscle Atrophy Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell MHC Class II Receptor Activity Polyubiquitin Modification-dependent Protein Binding Late Endosome Membrane Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Post-translational Protein Modification	Nucleus Protein Binding Negative Regulation Of Gene Expression DNA-binding Transcription Factor Binding Identical Protein Binding Chromatin Remodeling Chromatin Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Epigenetic Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process Regulation Of Gene Expression Axonemal A Tubule Inner Sheath Negative Regulation Of DNA-templated Transcription Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Cytoplasm Innate Immune Response PERK-mediated Unfolded Protein Response CHOP-ATF4 Complex Axonemal Microtubule DNA Deamination Chromatin RNA Metabolic Process Response To Radiation Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Macromolecule Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Regulation Of Signal Transduction By P53 Class Mediator Lewy Body Core Regulation Of Apoptotic Signaling Pathway Response To Growth Factor Response To Light Stimulus Defense Response To Symbiont Regulation Of Fatty Acid Beta-oxidation Response To Interleukin-1 Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Intracellular Signal Transduction Defense Response To Other Organism Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Translational Initiation
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