CTAG1B and LNPEP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTAG1B	LNPEP
Description		cancer/testis antigen 1B	leucyl and cystinyl aminopeptidase
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GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Lysosomal Membrane Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Aminopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding Metalloaminopeptidase Activity
	Biological Process	TRNA Threonylcarbamoyladenosine Metabolic Process	Protein Polyubiquitination Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Cell-cell Signaling Female Pregnancy Regulation Of Blood Pressure Neuropeptide Catabolic Process Protein Catabolic Process Negative Regulation Of Cold-induced Thermogenesis
Pathways			Endosomal/Vacuolar pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Ankylosing spondylitis ( 23749187) Birdshot chorioretinopathy ( 24957906) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233 28067908) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)
Interacting Genes		81 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1A CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MAGEC1 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX	37 interacting genes: AGT AQP6 ASGR2 BIK CD79A CGRRF1 CTAG1A CTAG1B CYB5R3 FAM210B FATE1 FCER1G FHOD1 FKBP7 GGT7 GPR42 GPX8 LCN2 LHFPL5 MMGT1 REEP4 REL SLC10A1 SLC2A4 SLC35E3 SLC39A9 SMAD9 SSMEM1 STOM TAS2R19 TCF4 TLCD4 TMEM35A TNKS TNKS2 UBQLN1 UNC93A
Entrez ID		1485	4012
HPRD ID		02151	01041
Ensembl ID		ENSG00000184033	ENSG00000113441
Uniprot IDs		P78358	Q9UIQ6
PDB IDs		1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1	4P8Q 4PJ6 4Z7I 5C97 5JHQ 5MJ6 7ZYF 8CGP 8CGW 8P0I
Enriched GO Terms of Interacting Partners?		Protein Binding Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Positive Regulation Of ERAD Pathway Antigen Processing And Presentation Of Exogenous Antigen Regulation Of ERAD Pathway MHC Class II Protein Complex Binding ER To Golgi Transport Vesicle Membrane Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Peptide Antigen Binding TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Myeloid Dendritic Cell Antigen Processing And Presentation Transport Vesicle Membrane Antigen Processing And Presentation Trans-Golgi Network Membrane Skeletal Muscle Atrophy Dendritic Cell Antigen Processing And Presentation Positive Regulation Of Proteasomal Protein Catabolic Process Clathrin-coated Endocytic Vesicle Membrane Protein Targeting To ER Regulation Of Protein Ubiquitination Skeletal Muscle Adaptation Striated Muscle Atrophy Lysosomal Membrane Endocytic Vesicle Membrane Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Autolysosome Membrane Muscle Atrophy Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell MHC Class II Receptor Activity Polyubiquitin Modification-dependent Protein Binding Late Endosome Membrane Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Post-translational Protein Modification	Membrane Positive Regulation Of Telomere Capping
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