CTAG1B and HLA-DRB5

Number of citations of the paper that reports this interaction (PMID 11782380)
13

Data Source:
HPRD (in vitro)

		CTAG1B	HLA-DRB5
Gene Name		cancer/testis antigen 1B	major histocompatibility complex, class II, DR beta 5
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Golgi Membrane Extracellular Space Lysosomal Membrane Plasma Membrane External Side Of Plasma Membrane ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Extracellular Vesicular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Peptide Antigen Binding
	Biological Process		Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response Inflammatory Response To Antigenic Stimulus Humoral Immune Response Mediated By Circulating Immunoglobulin Immune Response Detection Of Bacterium Cytokine-mediated Signaling Pathway Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II T Cell Costimulation Regulation Of Interleukin-4 Production Negative Regulation Of Interferon-gamma Production Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus T-helper 1 Type Immune Response Negative Regulation Of T Cell Proliferation T Cell Receptor Signaling Pathway Protein Tetramerization Interferon-gamma-mediated Signaling Pathway Regulation Of Interleukin-10 Secretion
Pathways			Generation of second messenger molecules Downstream TCR signaling Costimulation by the CD28 family Translocation of ZAP-70 to Immunological synapse Interferon Signaling Cytokine Signaling in Immune system Interferon gamma signaling TCR signaling MHC class II antigen presentation PD-1 signaling Phosphorylation of CD3 and TCR zeta chains Adaptive Immune System
Drugs
Diseases
GWAS			Chronic lymphocytic leukemia ( 21131588) Hypothyroidism ( 22493691) Lymphoma ( 23349640) Parkinson's disease ( 21292315) Prostate cancer ( 23535732) Ulcerative colitis ( 21297633 19122664)
Protein-Protein Interactions		6 interactors: HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 MAGEC1 UBQLN1	2 interactors: CTAG1B HLA-DRA
Entrez ID		1485	3127
HPRD ID		02151	09209
Ensembl ID		ENSG00000184033	ENSG00000198502
Uniprot IDs		P78358	Q30154
PDB IDs		2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3KLA	1FV1 1H15 1HQR 1ZGL
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II T Cell Receptor Signaling Pathway Interferon-gamma-mediated Signaling Pathway Antigen Receptor-mediated Signaling Pathway Cellular Response To Interferon-gamma Response To Interferon-gamma Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Cell-cell Adhesion Immune Response-activating Cell Surface Receptor Signaling Pathway Antigen Processing And Presentation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Cytokine-mediated Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Cellular Response To Cytokine Stimulus Regulation Of Cell Adhesion Positive Regulation Of Immune Response Response To Cytokine Innate Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Immune Response Regulation Of Immune System Process Defense Response Response To Stress Cellular Response To Organic Substance Immune System Process Polysaccharide Assembly With MHC Class II Protein Complex Response To Organic Substance Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Assembly Cell Surface Receptor Signaling Pathway Cellular Response To Stimulus Negative Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Interleukin-10 Secretion Detection Of Bacterium Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Response To Stimulus T-helper 1 Type Immune Response Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Polysaccharide Assembly With MHC Class II Protein Complex Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Assembly T Cell Costimulation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II T Cell Receptor Signaling Pathway Interferon-gamma-mediated Signaling Pathway Antigen Receptor-mediated Signaling Pathway Cellular Response To Interferon-gamma Response To Interferon-gamma Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Cell-cell Adhesion Immune Response-activating Cell Surface Receptor Signaling Pathway Antigen Processing And Presentation Cognition Regulation Of T Cell Activation Positive Regulation Of Cell Activation Cellular Protein Complex Assembly Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Cytokine-mediated Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Cellular Response To Cytokine Stimulus Regulation Of Cell Adhesion Cellular Macromolecular Complex Assembly Positive Regulation Of Immune Response Response To Cytokine
Tagcloud ?		acrbp antigens attractive chemoradiation ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas magea1 magea3 magea9 mainstay myxoid paraffin prame real round ssx2 testicular testis
Tagcloud (Difference) ?		acrbp antigens attractive chemoradiation ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas magea1 magea3 magea9 mainstay myxoid paraffin prame real round ssx2 testicular testis
Tagcloud (Intersection) ?