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SIRPA and KRT31
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SIRPA
KRT31
Gene Name
signal-regulatory protein alpha
keratin 31, type I
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Membrane
Integral Component Of Membrane
Extracellular Vesicular Exosome
Extracellular Space
Intermediate Filament
Extracellular Vesicular Exosome
Molecular Function
SH3 Domain Binding
Structural Constituent Of Cytoskeleton
Biological Process
Cell Adhesion
Blood Coagulation
Leukocyte Migration
Epidermis Development
Pathways
Signal regulatory protein (SIRP) family interactions
Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Aortic root size (
21223598
)
Mean platelet volume (
22139419
19820697
)
Protein-Protein Interactions
12 interactors:
CCDC57
CD47
IL1RAP
JAK2
KRT15
KRT31
KRT40
NOL3
PTPN11
PTPN6
TRIM2
TRIM27
181 interactors:
ABI2
AES
AGR2
ALDH3B1
ALS2CR11
AMOT
AMOTL2
ANKRD36BP1
AQP1
AQP5
ARHGAP35
ARMC7
ARSJ
ASMTL
ASPSCR1
ATG9A
ATN1
ATXN7L1
BEX2
BTC
BYSL
C12orf49
C19orf73
C1orf109
C1orf216
C5orf60
C6orf165
CA6
CARD9
CARKD
CATIP
CCDC112
CCDC120
CCDC17
CCDC93
CCER1
CCHCR1
CCNC
CD33
CDC20B
CDK18
CDKN1A
CEP57
CEP57L1
CEP70
CHCHD2
CHRNG
CLDN2
COA5
COMT
COX5A
COX5B
CRH
CTSG
DGCR6L
DHX37
DMRT3
DTNB
EIF4E2
EXOC8
FAM103A1
FAM110A
FAM124B
FAM71C
FAM74A4
FAM90A1
FARS2
FBF1
FBXW5
FKBP1B
FOXB1
GEM
GFOD1
GLRX3
GNAI2
GNE
GNG10
GNG5
GPS2
GSTP1
HAUS1
HDAC4
HGS
HOXA1
HSPA12B
HSPD1
ICAM4
INPP5D
INPP5K
INSR
JOSD1
KIFC3
KLC1
KLC4
KLHL38
KRT2
KRT5
KRT6A
KRT6B
KRT6C
KRT71
KRT77
KRT79
KRT8
KRT81
KRT83
LATS1
LCE4A
LENG1
LIN37
LINC00238
LINC00526
LMF2
LMO4
LONRF1
MAP3K7CL
MAPKBP1
MARK4
MRPL40
NAV1
NEK6
NPBWR2
OTUB2
P2RX7
PDE4DIP
PGLS
PIN1
PKN1
PPP1R18
PRF1
PRKAA2
PRR19
PSMA1
PSMG2
PSPC1
PTGER3
PTPMT1
RADIL
RCOR3
RIBC1
RPUSD3
RSPH14
SCNM1
SEMA4C
SHC3
SIRPA
SLC15A3
SLC23A1
SLC25A6
SMARCE1
SMCP
SMG9
SNAI1
SNRNP25
SPATA24
SPON2
SRSF2
SSX2IP
TAPBPL
THAP7
TMEM106C
TMEM231
TMSB4X
TRAF4
TROAP
TSG101
TTC23
TXLNA
USHBP1
UTP23
UXT
WDR25
WDYHV1
ZFYVE21
ZNF124
ZNF148
ZNF20
ZNF569
ZNF572
ZNF69
ZNRF2P1
Entrez ID
140885
3881
HPRD ID
03912
03047
Ensembl ID
ENSG00000198053
ENSG00000094796
Uniprot IDs
P78324
Q15323
PDB IDs
2JJS
2JJT
2UV3
2WNG
Enriched GO Terms of Interacting Partners
?
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Response To Interferon-gamma
Abortive Mitotic Cell Cycle
Response To Wounding
Positive Regulation Of Cell Activation
Regulation Of Cytokine-mediated Signaling Pathway
Innate Immune Response
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Interferon-gamma-mediated Signaling Pathway
Megakaryocyte Development
Blood Coagulation
Hemostasis
Cytokine-mediated Signaling Pathway
Cellular Response To Interferon-gamma
Regulation Of Cell Activation
Platelet Formation
Platelet Morphogenesis
Megakaryocyte Differentiation
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Response To Interferon-gamma
Growth Hormone Receptor Signaling Pathway
Cellular Response To Growth Hormone Stimulus
Regulation Of Body Fluid Levels
Cellular Response To Cytokine Stimulus
Negative Regulation Of Cell Adhesion
Wound Healing
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Regulation Of Cell Adhesion
Immune System Process
Immune Response
Regulation Of Immune System Process
Leukocyte Migration
Negative Regulation Of Adaptive Immune Response
Response To Stress
Defense Response
Regulation Of Cell Adhesion Mediated By Integrin
Positive Regulation Of Cell-cell Adhesion
Regulation Of Innate Immune Response
Response To Growth Hormone
Myeloid Cell Differentiation
Regulation Of Type I Interferon-mediated Signaling Pathway
Response To Cytokine
Regulation Of Protein Kinase Activity
Platelet-derived Growth Factor Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Regulation Of T Cell Activation
Regulation Of Kinase Activity
JAK-STAT Cascade
Cellular Process
Organelle Organization
Epidermis Development
Anatomical Structure Development
Developmental Process
Negative Regulation Of Cellular Metabolic Process
Cytoskeleton Organization
Positive Regulation Of Urine Volume
G2/M Transition Of Mitotic Cell Cycle
Gene Expression
Regulation Of Body Fluid Levels
Epithelium Development
RNA Metabolic Process
Regulation Of Interleukin-6 Production
Carbon Dioxide Transport
Response To Organic Substance
Regulation Of Glycolytic Process
Mitotic Cell Cycle Process
Hippo Signaling
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Interleukin-6 Production
Cell Cycle
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Stress-activated MAPK Cascade
Pancreatic Juice Secretion
Microtubule Cytoskeleton Organization
Movement Of Cell Or Subcellular Component
Mitotic Cell Cycle Phase Transition
Regulation Of Mitotic Nuclear Division
Regulation Of MAPK Cascade
Regulation Of Cell Cycle
Regulation Of Generation Of Precursor Metabolites And Energy
Cell Cycle Phase Transition
Multicellular Organismal Development
Bicarbonate Transport
Cell Volume Homeostasis
Cell Death
Death
Interaction With Symbiont
Negative Regulation Of Signaling
Transcription, DNA-templated
Mitotic Cell Cycle
Regulation Of Protein Metabolic Process
Apoptotic Process
Negative Regulation Of Protein Serine/threonine Kinase Activity
Response To Fungus
Cellular Response To Extracellular Stimulus
Cellular Metabolic Process
Programmed Cell Death
RNA Biosynthetic Process
Tagcloud
?
accelerated
cd47
concert
demonstrates
diabetogenic
displayed
drive
drives
enables
encodes
idd13
idd5
immunopathogenesis
insight
insulitis
islet
locus
mechanistic
nod
paired
potency
potentiate
recapitulates
restricted
t1d
transgene
variations
Tagcloud (Difference)
?
accelerated
cd47
concert
demonstrates
diabetogenic
displayed
drive
drives
enables
encodes
idd13
idd5
immunopathogenesis
insight
insulitis
islet
locus
mechanistic
nod
paired
potency
potentiate
recapitulates
restricted
t1d
transgene
variations
Tagcloud (Intersection)
?