CRMP1 and TRIP13

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CRMP1	TRIP13
Gene Name		collapsin response mediator protein 1	thyroid hormone receptor interactor 13
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Spindle Cytosol Dendrite Neuronal Cell Body	Male Germ Cell Nucleus Nucleus
	Molecular Function	Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides	Transcription Cofactor Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance	Oocyte Maturation Double-strand Break Repair Transcription From RNA Polymerase II Promoter Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Regulation Of Nucleic Acid-templated Transcription
Pathways		Axon guidance Semaphorin interactions CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494)
Protein-Protein Interactions		78 interactors: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LSM2 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1D1 ZAK ZNF24	75 interactors: ADAM15 AMDHD2 ARL11 ARSA ASB13 C11orf54 C4orf33 CARD14 CCBL1 CD99 COMT CPSF3L CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1BP MAD2L2 METTL15 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 PARK2 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA QARS RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TLDC1 TNRC6A TPT1 WDYHV1 ZNF34 ZNF655
Entrez ID		1400	9319
HPRD ID		03913	05145
Ensembl ID		ENSG00000072832	ENSG00000071539
Uniprot IDs		B3KT07 E9PD68 Q14194 Q96I11	Q15645
PDB IDs		4B3Z
Enriched GO Terms of Interacting Partners?		Cell Death Death Developmental Process Apoptotic Process Programmed Cell Death Anatomical Structure Development Regulation Of Cellular Protein Metabolic Process Cell Differentiation Catabolic Process Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Cellular Response To Stress Regulation Of Cell Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Proteolysis Regulation Of Cysteine-type Endopeptidase Activity Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cellular Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Organic Substance Protein Homooligomerization Response To Stress Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Nitrogen Compound Metabolic Process Cellular Response To Stimulus Multicellular Organismal Development Cytoskeleton Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Cellular Process Stress-activated MAPK Cascade Nervous System Development Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Cysteine-type Endopeptidase Activity System Development Positive Regulation Of Catalytic Activity Postreplication Repair Regulation Of Cellular Component Organization Protein Oligomerization Cellular Macromolecule Catabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Protein Complex Assembly Heterocycle Metabolic Process	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Stem Cell Differentiation Catabolic Process Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phospholipid Scrambling Regulation Of Epithelial To Mesenchymal Transition Metabolic Process Endomembrane System Organization Regulation Of SMAD Protein Import Into Nucleus Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Phospholipid Transport Carboxylic Acid Catabolic Process Negative Regulation Of Protein Metabolic Process Small Molecule Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Programmed Cell Death Dopamine Metabolic Process Regulation Of Protein Autophosphorylation Positive Regulation Of Homocysteine Metabolic Process RRNA Base Methylation Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Glutaminyl-tRNA Aminoacylation Lipid Hydroperoxide Transport Positive Regulation Of Intracellular Cholesterol Transport UDP-glucose Catabolic Process Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Cellular Response To Phosphate Starvation Male Meiosis Chromosome Separation Regulation Of Protein Metabolic Process Negative Regulation Of Cell Death Negative Regulation Of Phosphorylation Protein Ubiquitination Regulation Of Apoptotic Process
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Intersection) ?