CRMP1 and HNRNPH1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CRMP1	HNRNPH1
Gene Name		collapsin response mediator protein 1	heterogeneous nuclear ribonucleoprotein H1 (H)
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Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Spindle Cytosol Dendrite Neuronal Cell Body	Nucleus Nucleoplasm Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides	Nucleotide Binding RNA Binding Protein Binding Poly(U) RNA Binding Poly(A) RNA Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Gene Expression Regulation Of RNA Splicing
Pathways		Axon guidance Semaphorin interactions CRMPs in Sema3A signaling	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494)
Protein-Protein Interactions		78 interactors: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LSM2 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1D1 ZAK ZNF24	21 interactors: APBB1 CRMP1 DDX5 ERG HIPK3 HNRNPF HNRNPH3 KHSRP NCBP1 NCBP2 NDRG1 PIN1 RALY SF1 SF3B4 SREK1 SUMO4 TCERG1 TOM1L1 YWHAG YWHAQ
Entrez ID		1400	3187
HPRD ID		03913	03021
Ensembl ID		ENSG00000072832	ENSG00000169045
Uniprot IDs		B3KT07 E9PD68 Q14194 Q96I11	E9PCY7 G8JLB6 P31943
PDB IDs		4B3Z	2LXU
Enriched GO Terms of Interacting Partners?		Cell Death Death Developmental Process Apoptotic Process Programmed Cell Death Anatomical Structure Development Regulation Of Cellular Protein Metabolic Process Cell Differentiation Catabolic Process Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Cellular Response To Stress Regulation Of Cell Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Proteolysis Regulation Of Cysteine-type Endopeptidase Activity Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cellular Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Organic Substance Protein Homooligomerization Response To Stress Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Nitrogen Compound Metabolic Process Cellular Response To Stimulus Multicellular Organismal Development Cytoskeleton Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Cellular Process Stress-activated MAPK Cascade Nervous System Development Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Cysteine-type Endopeptidase Activity System Development Positive Regulation Of Catalytic Activity Postreplication Repair Regulation Of Cellular Component Organization Protein Oligomerization Cellular Macromolecule Catabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Protein Complex Assembly Heterocycle Metabolic Process	RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Cis Splicing, Via Spliceosome Cellular Metabolic Process Regulation Of MRNA Processing Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of RNA Splicing MRNA Transport Histone MRNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Gene Expression RNA Transport Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Localization Regulation Of Viral Process MRNA Catabolic Process 7-methylguanosine MRNA Capping Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Ribonucleoprotein Complex Assembly 7-methylguanosine RNA Capping RNA Catabolic Process Termination Of RNA Polymerase II Transcription Intrinsic Apoptotic Signaling Pathway Spliceosomal SnRNP Assembly Positive Regulation Of Viral Transcription Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Thymidylate Synthase Biosynthetic Process Negative Regulation Of Potassium Ion Export Peptidyl-amino Acid Modification Positive Regulation Of Intracellular Transport Positive Regulation Of Mitochondrion Organization Apoptotic Process Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	cct5 cd68 ddx5 enterovirus ft1dm fulminant helicase hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	cct5 cd68 ddx5 enterovirus ft1dm fulminant helicase hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 samhd1 serpin serpinb6 tymp wars
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