CRMP1 and DDX18

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CRMP1	DDX18
Gene Name		collapsin response mediator protein 1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Spindle Cytosol Dendrite Neuronal Cell Body	Nucleolus Membrane
	Molecular Function	Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance	Metabolic Process
Pathways		Axon guidance Semaphorin interactions CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494)
Protein-Protein Interactions		78 interactors: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LSM2 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1D1 ZAK ZNF24	4 interactors: APP CRMP1 INADL MTA1
Entrez ID		1400	8886
HPRD ID		03913	05894
Ensembl ID		ENSG00000072832	ENSG00000088205
Uniprot IDs		B3KT07 E9PD68 Q14194 Q96I11	Q8N254 Q9NVP1
PDB IDs		4B3Z	3LY5
Enriched GO Terms of Interacting Partners?		Cell Death Death Developmental Process Apoptotic Process Programmed Cell Death Anatomical Structure Development Regulation Of Cellular Protein Metabolic Process Cell Differentiation Catabolic Process Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Cellular Response To Stress Regulation Of Cell Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Proteolysis Regulation Of Cysteine-type Endopeptidase Activity Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cellular Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Organic Substance Protein Homooligomerization Response To Stress Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Nitrogen Compound Metabolic Process Cellular Response To Stimulus Multicellular Organismal Development Cytoskeleton Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Cellular Process Stress-activated MAPK Cascade Nervous System Development Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Cysteine-type Endopeptidase Activity System Development Positive Regulation Of Catalytic Activity Postreplication Repair Regulation Of Cellular Component Organization Protein Oligomerization Cellular Macromolecule Catabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Protein Complex Assembly Heterocycle Metabolic Process	Positive Regulation Of Protein Autoubiquitination Synaptic Growth At Neuromuscular Junction Regulation Of Protein Autoubiquitination Collateral Sprouting In Absence Of Injury Locomotory Behavior Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Response To Light Stimulus Pyrimidine Nucleobase Catabolic Process Neuron Remodeling Locomotor Rhythm Axon Guidance Response To External Stimulus Response To Radiation Single-organism Behavior Axonogenesis Circadian Behavior Cellular Copper Ion Homeostasis Rhythmic Behavior Axon Development Cell Morphogenesis Involved In Neuron Differentiation Behavior Chemotaxis Entrainment Of Circadian Clock By Photoperiod Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Projection Morphogenesis Photoperiodism Entrainment Of Circadian Clock Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Morphogenesis Involved In Differentiation Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Pyrimidine Nucleobase Metabolic Process RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuron Projection Development Cell Projection Morphogenesis Ionotropic Glutamate Receptor Signaling Pathway Cell Part Morphogenesis Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Tight Junction Assembly Axon Cargo Transport
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	advance aromatase bioinformatic chipseq coactivator concise contexts coregulatory defines doi endocrine helicase hmgb2 integration october oestrogen onc online partners publication resistant reveals setting src steroid switch switched tamoxifen verified
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	advance aromatase bioinformatic chipseq coactivator concise contexts coregulatory defines doi endocrine helicase hmgb2 integration october oestrogen onc online partners publication resistant reveals setting src steroid switch switched tamoxifen verified
Tagcloud (Intersection) ?