PTRH1 and FAM9B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PTRH1	FAM9B
Description		peptidyl-tRNA hydrolase 1 homolog	family with sequence similarity 9 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm
	Molecular Function	TRNA Binding RNA Binding Peptidyl-tRNA Hydrolase Activity Protein Binding Hydrolase Activity	Protein Binding
	Biological Process	Rescue Of Stalled Ribosome	Spermatid Development Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS			Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: ANKRD28 FAM9B LCN2 PICK1 PRNP	140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614
Entrez ID		138428	171483
HPRD ID		12936	15955
Ensembl ID		ENSG00000187024	ENSG00000177138
Uniprot IDs		C9J7Z1 Q86Y79	Q8IZU0
PDB IDs
Enriched GO Terms of Interacting Partners?		Dendritic Spine Maintenance Long-term Memory Neuron Projection Organization Dendritic Spine Organization Postsynapse Organization Cellular Response To Amyloid-beta Positive Regulation Of Neuron Apoptotic Process Response To Amyloid-beta Cellular Component Maintenance Positive Regulation Of Hippocampal Neuron Apoptotic Process Type 8 Metabotropic Glutamate Receptor Binding Positive Regulation Of Iron Ion Import Across Plasma Membrane Protease Binding Enterobactin Binding Memory Positive Regulation Of Endothelial Tube Morphogenesis Iron Ion Sequestering Activity Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Siderophore Transport Cytoplasmic Vesicle Lumen Negative Regulation Of Hippocampal Neuron Apoptotic Process Response To Kainic Acid Type 5 Metabotropic Glutamate Receptor Binding Membrane Curvature Sensor Activity Response To Herbicide Regulation Of Hippocampal Neuron Apoptotic Process Response To Mycotoxin Regulation Of Synaptic Plasticity Negative Regulation Of Dendritic Spine Maintenance Cupric Ion Binding Regulation Of Iron Ion Transport Response To Blue Light Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Cellular Component Organization Response To Iron(II) Ion Regulation Of Endothelial Tube Morphogenesis ATP-dependent Protein Binding Aspartic-type Endopeptidase Inhibitor Activity Regulation Of Neuron Apoptotic Process Cellular Response To Nutrient Levels Postsynaptic Density Regulation Of Monoatomic Cation Transmembrane Transport Negative Regulation Of Actin Nucleation Learning Or Memory Cellular Response To X-ray Positive Regulation Of Cellular Component Organization Response To Xenobiotic Stimulus Regulation Of Monoatomic Ion Transmembrane Transport Response To Fructose	Protein Binding Mitochondrial Matrix RNA Binding
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