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CR2 and HNRNPU
Number of citations of the paper that reports this interaction (PubMedID
7753047
)
0
Data Source:
HPRD
(in vitro)
CR2
HNRNPU
Description
complement C3d receptor 2
heterogeneous nuclear ribonucleoprotein U
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
Membrane
Receptor Complex
Extracellular Exosome
Nuclear Chromosome
Chromosome, Centromeric Region
Kinetochore
Spindle Pole
Nucleus
Nucleoplasm
Spliceosomal Complex
Chromosome
Telomerase Holoenzyme Complex
Cytoplasm
Centrosome
Spindle
Cytosol
Cytoskeleton
Cell Surface
Membrane
Nuclear Matrix
Nuclear Speck
Dendrite
Midbody
Protein-containing Complex
Cytoplasmic Ribonucleoprotein Granule
CRD-mediated MRNA Stability Complex
Catalytic Step 2 Spliceosome
Mitotic Spindle
RNA Polymerase II Transcription Regulator Complex
Inactive Sex Chromosome
Mitotic Spindle Midzone
Mitotic Spindle Microtubule
Ribonucleoprotein Complex
Molecular Function
Virus Receptor Activity
Complement Binding
DNA Binding
Complement Receptor Activity
Transmembrane Signaling Receptor Activity
Protein Binding
Immunoglobulin Receptor Binding
Protein Homodimerization Activity
Nucleotide Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Complex Binding
TFIIH-class Transcription Factor Complex Binding
DNA Binding
Chromatin Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Transcription Corepressor Activity
RNA Binding
Double-stranded RNA Binding
Single-stranded RNA Binding
MRNA 3'-UTR Binding
Actin Binding
Protein Binding
ATP Binding
Poly(A) Binding
SnRNA Binding
Poly(C) RNA Binding
Chromatin DNA Binding
Poly(G) Binding
PiRNA Binding
Pre-mRNA Binding
Identical Protein Binding
Ribonucleoprotein Complex Binding
Sequence-specific DNA Binding
Protein-containing Complex Binding
Telomerase RNA Binding
RNA Polymerase II C-terminal Domain Binding
LncRNA Binding
Sequence-specific Double-stranded DNA Binding
Promoter-specific Chromatin Binding
Biological Process
Immune System Process
Complement Receptor Mediated Signaling Pathway
T Cell Mediated Immunity
Immune Response
Complement Activation, Alternative Pathway
Complement Activation, Classical Pathway
B Cell Differentiation
B Cell Proliferation
B Cell Activation
Innate Immune Response
Negative Regulation Of Complement Activation, Classical Pathway
Symbiont Entry Into Host Cell
Type I Interferon-mediated Signaling Pathway
Antiviral Innate Immune Response
Negative Regulation Of Transcription By RNA Polymerase II
Alternative MRNA Splicing, Via Spliceosome
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Osteoblast Differentiation
Chromatin Organization
RNA Processing
MRNA Processing
Regulation Of Mitotic Cell Cycle
RNA Splicing
Dosage Compensation By Inactivation Of X Chromosome
Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
MRNA Metabolic Process
Cell Differentiation
Erythrocyte Differentiation
Regulatory NcRNA-mediated Heterochromatin Formation
Negative Regulation Of Telomere Maintenance Via Telomerase
Circadian Regulation Of Gene Expression
Negative Regulation Of Kinase Activity
Negative Regulation Of Transcription Elongation By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
MRNA Stabilization
Rhythmic Process
Cell Division
Maintenance Of Protein Location In Nucleus
Cardiac Muscle Cell Development
Random Inactivation Of X Chromosome
CRD-mediated MRNA Stabilization
Cellular Response To Glucocorticoid Stimulus
Positive Regulation Of Brown Fat Cell Differentiation
Dendritic Transport Of Messenger Ribonucleoprotein Complex
Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Regulation Of Mitotic Spindle Assembly
Regulation Of Chromatin Organization
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Protein Localization To Spindle Microtubule
RNA Localization To Chromatin
Cellular Response To Leukemia Inhibitory Factor
Adaptive Thermogenesis
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Positive Regulation Of Stem Cell Proliferation
Negative Regulation Of Stem Cell Differentiation
Positive Regulation Of Cytoplasmic Translation
Pathways
Regulation of Complement cascade
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
Drugs
Diseases
GWAS
Alzheimer's disease or fasting insulin levels (pleiotropy) (
30805717
)
Refractive error (
32231278
)
Systemic sclerosis (
29293537
)
Type 2 diabetes (
21490949
)
Interacting Genes
11 interacting genes:
ANXA6
C3
CD19
CR1
FCER2
FHOD1
HNRNPU
IFITM1
IFNA1
NCOA1
TP53
42 interacting genes:
ACTB
BTRC
CASP3
CD5
CDKN2A
CEBPA
CR2
DUX4
ELL
EP300
ERG
GRIN1
GRIN2D
GTF2H1
HMGB1
HNRNPH3
HSPB1
IL7R
KAT2B
LINC00624
NDN
NDRG1
NEDD4
NR3C1
NRON
PIN1
PLK1
POU3F4
PRMT1
PRPF40A
PTPN11
RBPMS2
SMN1
SREK1
STAU1
SUMO2
SYK
TCERG1
UBE2I
WBP4
YAP1
ZNF689
Entrez ID
1380
3192
HPRD ID
00399
04185
Ensembl ID
ENSG00000117322
ENSG00000153187
Uniprot IDs
P20023
Q00839
Q96BA7
PDB IDs
1GHQ
1LY2
1W2R
1W2S
2ATY
2GSX
3OED
8SM0
8ZNI
Enriched GO Terms of Interacting Partners
?
Immune Effector Process
Positive Regulation Of Humoral Immune Response
Positive Regulation Of Activation Of Membrane Attack Complex
Regulation Of Humoral Immune Response
Protein-containing Complex
Positive Regulation Of Complement Activation
Interferon-mediated Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Leukocyte Activation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Activation
Complement Receptor Mediated Signaling Pathway
Complement Activation, Alternative Pathway
Immune Response
Immune System Process
Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Immune Response-activating Signaling Pathway
Lymphocyte Activation Involved In Immune Response
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Complement Activation
Immune Response-regulating Signaling Pathway
Activation Of Immune Response
Leukocyte Activation Involved In Immune Response
Signal Transduction
Cell Activation Involved In Immune Response
Negative Regulation Of Catalytic Activity
Lymphocyte Activation
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Regulation Of ATP-dependent Activity
B Cell Activation
Complement Activation, Classical Pathway
Regulation Of Lymphocyte Mediated Immunity
Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Negative Regulation Of Telomere Maintenance
Positive Regulation Of Immunoglobulin Mediated Immune Response
Regulation Of Adaptive Immune Response
Regulation Of Telomere Maintenance Via Telomerase
Response To Other Organism
Positive Regulation Of Immune Response
Positive Regulation Of Immune Effector Process
Innate Immune Response
Complement Activation
C5L2 Anaphylatoxin Chemotactic Receptor Binding
Humoral Immune Response
Complement Component C3b Receptor Activity
Immune Complex Clearance By Erythrocytes
Complement Component C4b Receptor Activity
Negative Regulation Of Serine-type Endopeptidase Activity
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Nucleoplasm
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Metabolic Process
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Biosynthetic Process
Nucleus
Regulation Of Transcription By RNA Polymerase II
Regulation Of Primary Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Leukocyte Cell-cell Adhesion
Regulation Of T Cell Activation
Intracellular Signal Transduction
Postsynaptic Cytosol
Developmental Process
RNA Binding
Protein-containing Complex
Cellular Response To Stress
Regulation Of Cell Activation
Positive Regulation Of T Cell Activation
Regulation Of Cell-cell Adhesion
Regulation Of Lymphocyte Activation
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Positive Regulation Of Cell Activation
Negative Regulation Of Immune System Process
Positive Regulation Of Leukocyte Cell-cell Adhesion
Macromolecule Metabolic Process
Cellular Response To Oxygen-containing Compound
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of T Cell Differentiation
Negative Regulation Of Macromolecule Biosynthetic Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Hemopoiesis
Signal Transduction
Negative Regulation Of Metabolic Process
Response To Amino Acid
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Tagcloud (Intersection)
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