MT-ATP6 and FANCC

Number of citations: 0 (PubMedID 14499622)
Data Source: BioGRID (two hybrid)

		MT-ATP6	FANCC
Name		ATP synthase F0 subunit 6	FA complementation group C
Structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Proton-transporting ATP Synthase Complex	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton Channel Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Protein Binding
	Biological Process	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Response To Hyperoxia Proton Transmembrane Transport	DNA Repair Nucleotide-excision Repair DNA Damage Response Cellular Response To Oxidative Stress Interstrand Cross-link Repair Protein-containing Complex Assembly
Pathways		Formation of ATP by chemiosmotic coupling Mitochondrial translation termination Cristae formation Mitochondrial protein degradation	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes PKR-mediated signaling
Drugs		Estradiol Estradiol acetate Estradiol benzoate Estradiol cypionate Estradiol dienanthate Estradiol valerate	None
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)	Fanconi anemia
GWAS		No GWAS studies recorded	Birth weight ( 31043758 ) Hematocrit ( 32888494 ) Offspring birth weight ( 31043758 ) Polycystic ovary syndrome ( 26284813 )
Interacting Genes		3 interacting genes: CPEB2 FANCC GLP1R	54 interacting genes: APC AZIN1 BMPR1A BUB1 CAPN10 CCNA2 CCND1 CDK1 CTBP1 DLC1 DNAJB1 EGFR FANCA FANCD2 FANCE FANCF FANCG FBXW7 GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRAS KRT1 MEOX2 MLH3 MT-ATP6 MUTYH NRAS PDGFRL PIK3CA PMS2 POR PRDX3 PRPF31 PTPN12 PTPRJ RB1 RPL18 RPS3A SMAD4 SPTA1 SPTAN1 SRC STAT1 STMN1 STMN2 TCERG1 TGFBR2 USP14 ZBTB32
Entrez ID		4508	2176
HPRD ID		02472	01967
Ensembl ID		ENSG00000198899	ENSG00000158169
Uniprot IDs		P00846 Q0ZFE3	A0A024R9N2 A0A087WW44 B4E3W2 Q00597
PDB IDs		8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3	7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
GO Terms Enriched among Interactors		Cellular Response To Peptide Hormone Stimulus Glucagon-like Peptide 1 Receptor Activity Glucagon Receptor Activity Negative Regulation Of Cytoplasmic Translational Elongation Response To Psychosocial Stress Response To Peptide Hormone Negative Regulation Of Translational Elongation Cellular Response To Hormone Stimulus Fanconi Anaemia Nuclear Complex Post-translational Protein Targeting To Membrane, Translocation Positive Regulation Of Lyase Activity Cellular Response To Glucagon Stimulus Positive Regulation Of Adenylate Cyclase Activity Activation Of Adenylate Cyclase Activity Positive Regulation Of Cyclase Activity Response To Glucagon Response To Hormone Translation Factor Activity, RNA Binding GTPase Inhibitor Activity Negative Regulation Of Cytoplasmic Translation Ribosomal Small Subunit Binding MRNA Regulatory Element Binding Translation Repressor Activity Ribosomal Large Subunit Binding Regulation Of Translational Elongation Translation Regulator Activity MRNA 3'-UTR AU-rich Region Binding Intracellular Protein Transmembrane Transport Positive Regulation Of Blood Pressure Response To Stress Regulation Of Cytoplasmic Translation Peptide Hormone Binding G Protein-coupled Peptide Receptor Activity Interstrand Cross-link Repair Cellular Response To Oxygen-containing Compound Negative Regulation Of Blood Pressure Nucleotide-excision Repair Ribosome Binding Protein Transmembrane Transport	Cytosol Regulation Of Programmed Cell Death Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Negative Regulation Of Supramolecular Fiber Organization Cellular Response To Stress Response To Stress Cellular Response To Growth Factor Stimulus Negative Regulation Of Cellular Component Organization Negative Regulation Of Cytoskeleton Organization Response To Hormone Response To Growth Factor Fanconi Anaemia Nuclear Complex Cellular Response To Peptide Hormone Stimulus ATP-dependent Protein Folding Chaperone Cellular Response To Hormone Stimulus Interstrand Cross-link Repair Nucleoplasm Regulation Of Supramolecular Fiber Organization Response To Steroid Hormone Regulation Of Organelle Organization Negative Regulation Of Programmed Cell Death Cadherin Binding Positive Regulation Of Cell Population Proliferation Nucleus Focal Adhesion Protein Folding Chaperone Negative Regulation Of Apoptotic Process Cellular Response To Oxygen-containing Compound Regulation Of Multicellular Organismal Process DNA Repair Regulation Of Immune System Process Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Protein-containing Complex Disassembly DNA Damage Response Intracellular Signal Transduction Response To Peptide Hormone Regulation Of Cytoskeleton Organization Response To Lipid G1/S Transition Of Mitotic Cell Cycle Nucleic Acid Metabolic Process Macromolecule Metabolic Process Regulation Of Protein-containing Complex Assembly Negative Regulation Of Cell Cycle Phase Transition Cell Cycle G1/S Phase Transition Response To Unfolded Protein Regulation Of Cellular Component Organization Regulation Of Cell Cycle Phase Transition Regulation Of Protein Depolymerization