MT-ATP6

Description		ATP synthase F0 subunit 6
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Proton-transporting ATP Synthase Complex
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton Channel Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Response To Hyperoxia Proton Transmembrane Transport
Pathways		Formation of ATP by chemiosmotic coupling Mitochondrial translation termination Cristae formation Mitochondrial protein degradation
Drugs		Estradiol Estradiol acetate Estradiol benzoate Estradiol cypionate Estradiol dienanthate Estradiol valerate
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS
Interacting Genes		3 interacting genes: CPEB2 FANCC GLP1R
Entrez ID		4508
HPRD ID		02472
Ensembl ID		ENSG00000198899
Uniprot IDs		P00846 Q0ZFE3
PDB IDs		8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3
Enriched GO Terms of Interacting Partners?		Cellular Response To Peptide Hormone Stimulus Glucagon-like Peptide 1 Receptor Activity Glucagon Receptor Activity Negative Regulation Of Cytoplasmic Translational Elongation Response To Psychosocial Stress Response To Peptide Hormone Negative Regulation Of Translational Elongation Cellular Response To Hormone Stimulus Fanconi Anaemia Nuclear Complex Post-translational Protein Targeting To Membrane, Translocation Positive Regulation Of Lyase Activity Cellular Response To Glucagon Stimulus Positive Regulation Of Adenylate Cyclase Activity Activation Of Adenylate Cyclase Activity Positive Regulation Of Cyclase Activity Response To Glucagon Response To Hormone Translation Factor Activity, RNA Binding GTPase Inhibitor Activity Negative Regulation Of Cytoplasmic Translation Ribosomal Small Subunit Binding MRNA Regulatory Element Binding Translation Repressor Activity Ribosomal Large Subunit Binding Regulation Of Translational Elongation Translation Regulator Activity MRNA 3'-UTR AU-rich Region Binding Intracellular Protein Transmembrane Transport Positive Regulation Of Blood Pressure Response To Stress Regulation Of Cytoplasmic Translation Peptide Hormone Binding G Protein-coupled Peptide Receptor Activity Interstrand Cross-link Repair Cellular Response To Oxygen-containing Compound Negative Regulation Of Blood Pressure Nucleotide-excision Repair Ribosome Binding Protein Transmembrane Transport
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