UBR3 and DZIP3

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		UBR3	DZIP3
Gene Name		ubiquitin protein ligase E3 component n-recognin 3 (putative)	DAZ interacting zinc finger protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Phosphatase Binding Polyubiquitin Binding Poly(A) RNA Binding
	Biological Process	In Utero Embryonic Development Suckling Behavior Ubiquitin-dependent Protein Catabolic Process Sensory Perception Of Smell Embryo Development Protein Ubiquitination Olfactory Behavior	Protein Polyubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: DZIP3 UBC UBE2A UBE2B	42 interactors: AKTIP AP1M1 ARHGAP32 ATXN1 BIRC2 BIRC3 CEP63 DAZ1 GTF2H2C_2 HNRNPF HNRNPUL1 HOTAIR NCOR1 PCGF3 RAD18 RBM4B RNF38 TOLLIP TRIM21 TSG101 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765
Entrez ID		130507	9666
HPRD ID		15887	10562
Ensembl ID		ENSG00000144357	ENSG00000198919
Uniprot IDs		Q6ZT12	Q86Y13
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Histone H2A Ubiquitination Postreplication Repair Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Proteasomal Protein Catabolic Process Histone Ubiquitination Protein K48-linked Ubiquitination Protein Autoubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process DNA Repair Protein Catabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Response To UV Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I DNA Metabolic Process Cellular Protein Modification Process Response To Abiotic Stimulus Negative Regulation Of Histone Phosphorylation Positive Regulation Of Reciprocal Meiotic Recombination Maintenance Of Chromatin Silencing Positive Regulation Of Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Cell Cycle Antigen Processing And Presentation Response To Hypoxia Positive Regulation Of Meiosis I Cellular Response To Stress Proteolysis Cellular Protein Metabolic Process Response To Light Stimulus Negative Regulation Of CAMP-mediated Signaling Chiasma Assembly Regulation Of Meiosis I Histone Modification Catabolic Process Sperm Axoneme Assembly Viral Protein Processing Response To Radiation Regulation Of Cell Cycle Process In Utero Embryonic Development Protein Metabolic Process Positive Regulation Of Meiotic Nuclear Division Chromatin Modification	Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Toll-like Receptor 4 Signaling Pathway Protein K11-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Protein Metabolic Process Activation Of Innate Immune Response Cellular Metabolic Process Positive Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Innate Immune Response Protein Monoubiquitination Proteolysis Protein Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Protein Ubiquitination DNA Repair Regulation Of Metabolic Process Innate Immune Response Immune Response-regulating Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Stress Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Postreplication Repair Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Process
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