MITD1 and CHMP2A

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo)

		MITD1	CHMP2A
Gene Name		MIT, microtubule interacting and transport, domain containing 1	charged multivesicular body protein 2A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extrinsic Component Of Membrane Midbody Late Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Cytosol Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Protein Homodimerization Activity	Protein Binding Protein Domain Specific Binding
	Biological Process	Mitotic Cytokinesis Cell Separation After Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Multivesicular Body Sorting Pathway	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation
Pathways			HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		4 interactors: ATF7 CHMP2A CHMP5 ZFYVE19	12 interactors: CHMP3 DOCK8 E2F4 EIF2B5 MITD1 NOL4 STAMBP TGFB3 USP54 USP8 VPS4A VPS4B
Entrez ID		129531	27243
HPRD ID		14044	12520
Ensembl ID		ENSG00000158411	ENSG00000130724
Uniprot IDs		Q8WV92	O43633
PDB IDs		2YMB 4A5X 4A5Z
Enriched GO Terms of Interacting Partners?		Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Cell Separation After Cytokinesis Regulation Of Cell Division Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Cell Division Regulation Of Centrosome Cycle Regulation Of Cell Cycle Process Viral Process Vacuolar Transport Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Nucleus Organization Regulation Of Mitotic Nuclear Division Negative Regulation Of Centriole Elongation Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Cycle Regulation Of Microtubule-based Process Viral Life Cycle Endosomal Transport Chromosome Segregation Negative Regulation Of Centriole Replication Abscission Mitotic Nuclear Division Viral Budding Via Host ESCRT Complex Establishment Of Organelle Localization Regulation Of Protein Complex Assembly Positive Regulation Of Viral Release From Host Cell Viral Budding Negative Regulation Of Cytokinesis Regulation Of Mitotic Cell Cycle Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Organelle Localization Regulation Of Centriole Replication Negative Regulation Of Cell Cycle Regulation Of Cytoskeleton Organization Negative Regulation Of Centrosome Duplication Regulation Of Viral Release From Host Cell Virion Assembly Mitotic Cell Cycle Process Regulation Of Receptor Recycling Endosome To Lysosome Transport Mitotic Cell Cycle Membrane Organization Lysosomal Transport	Cell Separation After Cytokinesis Cell Division Cytokinesis Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Cytokinesis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Cycle Process Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Viral Budding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cell Cycle Regulation Of Viral Release From Host Cell Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic Metaphase Plate Congression Viral Life Cycle Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Endosome Organization Metaphase Plate Congression Endosomal Transport Protein Catabolic Process Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Cell Division Regulation Of Centrosome Cycle Proteolysis Positive Regulation Of Exocytosis Positive Regulation Of Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Exosomal Secretion Memory T Cell Proliferation Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Process Mitotic Sister Chromatid Segregation Membrane Budding Sister Chromatid Segregation Negative Regulation Of Cell Death Positive Regulation Of Centriole Replication Detection Of Hypoxia Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Uterine Wall Breakdown Ovulation Cycle Process Vacuole Organization Protein Deubiquitination
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