MITD1 and CARD10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MITD1	CARD10
Description		microtubule interacting and trafficking domain containing 1	caspase recruitment domain family member 10
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Membrane Midbody Late Endosome Membrane Extracellular Exosome	Immunological Synapse Cytoplasm CBM Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Identical Protein Binding	Protein Binding Signaling Receptor Complex Adaptor Activity
	Biological Process	Mitotic Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Cell Division Midbody Abscission Multivesicular Body Sorting Pathway	Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Macromolecule Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Immune Response Protein-containing Complex Assembly Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Autoimmune hepatitis type-1 ( 24768677) Low vWF levels ( 26486471) Optic disc area ( 21307088 25631615 28073927 31798171) Optic disc size ( 31809533) Refractive error ( 32231278) Vertical cup-disc ratio ( 25241763 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		17 interacting genes: ATF7 CARD10 CEBPA CHMP1A CHMP1B CHMP2A CHMP5 DSCAM GPHN KANK2 MCPH1 NTAQ1 RTN3 TRIM14 TTC33 ZFYVE19 ZNF655	105 interacting genes: ATXN7 BAHD1 BCL10 BCL6B C8orf48 CARD9 CATSPER1 CBX8 CCDC116 CCDC187 CDC37 CEP95 CHIC2 CNNM3 CWF19L2 CXCL16 CYSRT1 DHX57 DOCK2 DRC4 DUSP26 FAM47B FOXD4L3 GADD45GIP1 GFAP GIPC1 GPATCH2L GSE1 GSTP1 HBZ HOXB9 IKBKG IL16 JOSD1 KANK2 KDM1A KEAP1 KLHL12 KRT75 KRTAP10-8 KRTAP12-3 KRTAP26-1 KRTAP9-2 KRTAP9-3 LENG1 MAGOHB METTL17 MITD1 MYPOP NME7 OLIG3 PIBF1 PKP1 PNKP PRDM14 PRPF18 PRPF3 PRR35 PTCD1 PTGDS RIN1 SCNM1 SEMA3B SPATA18 SPMIP2 TBC1D22B TBC1D26 TFAP2D TMEM43 TRIM27 TRIM41 USP54 UTP14C ZBTB26 ZFP1 ZNF10 ZNF12 ZNF165 ZNF180 ZNF202 ZNF223 ZNF239 ZNF250 ZNF285 ZNF286A ZNF32 ZNF329 ZNF366 ZNF414 ZNF415 ZNF439 ZNF440 ZNF524 ZNF552 ZNF559 ZNF564 ZNF575 ZNF581 ZNF587 ZNF613 ZNF670 ZNF775 ZNF80 ZNF837 ZSCAN25
Entrez ID		129531	29775
HPRD ID		14044	06233
Ensembl ID		ENSG00000158411	ENSG00000100065
Uniprot IDs		Q8WV92	Q9BWT7
PDB IDs		2YMB 4A5X 4A5Z
Enriched GO Terms of Interacting Partners?		Mitotic Cytokinetic Process Midbody Abscission ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole ESCRT III Complex Disassembly ESCRT Complex Disassembly Cytokinetic Process Multivesicular Body-lysosome Fusion Viral Budding From Plasma Membrane Lysosomal Membrane Organization Regulation Of Centrosome Cycle Late Endosome To Lysosome Transport Kinetochore Microtubule Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Viral Budding Nuclear Membrane Reassembly Multivesicular Body Membrane Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Assembly Multivesicular Body Organization Regulation Of Spindle Assembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Multivesicular Body Mitotic Metaphase Chromosome Alignment Multivesicular Body Sorting Pathway Regulation Of Centrosome Duplication Nuclear Membrane Organization Autophagosome Maturation Regulation Of Cell Cycle Process Regulation Of Cell Cycle Autophagosome Membrane Metaphase Chromosome Alignment Membrane Assembly Midbody Chromosome Localization Endosome Organization Nuclear Pore Nucleus Organization Vesicle Fusion Organelle Membrane Fusion Regulation Of Microtubule-based Process Plasma Membrane Organization Lysosomal Transport	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process DNA Binding Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Protein Binding Regulation Of Metabolic Process Nucleus Intermediate Filament Metal Ion Binding DNA-binding Transcription Factor Activity Keratin Filament RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Identical Protein Binding CBM Complex
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