MITD1 and CHMP5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		MITD1	CHMP5
Description		microtubule interacting and trafficking domain containing 1	charged multivesicular body protein 5
Image
GO Annotations	Cellular Component	Endosome Membrane Midbody Late Endosome Membrane Extracellular Exosome	Autophagosome Membrane Kinetochore ESCRT III Complex Nucleus Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Membrane Midbody Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Identical Protein Binding	Protein Binding Cadherin Binding
	Biological Process	Mitotic Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Cell Division Midbody Abscission Multivesicular Body Sorting Pathway	Plasma Membrane Repair Regulation Of Receptor Recycling Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Lysosome Organization Mitotic Metaphase Chromosome Alignment Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Erythrocyte Differentiation Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Viral Budding From Plasma Membrane Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly
Pathways			Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		17 interacting genes: ATF7 CARD10 CEBPA CHMP1A CHMP1B CHMP2A CHMP5 DSCAM GPHN KANK2 MCPH1 NTAQ1 RTN3 TRIM14 TTC33 ZFYVE19 ZNF655	17 interacting genes: APPBP2 CEBPA CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91
Entrez ID		129531	51510
HPRD ID		14044	15408
Ensembl ID		ENSG00000158411	ENSG00000086065
Uniprot IDs		Q8WV92	Q9NZZ3
PDB IDs		2YMB 4A5X 4A5Z	2LXM 3ULY 3UM0 3UM1 3UM2 4TXR
Enriched GO Terms of Interacting Partners?		Mitotic Cytokinetic Process Midbody Abscission ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole ESCRT III Complex Disassembly ESCRT Complex Disassembly Cytokinetic Process Multivesicular Body-lysosome Fusion Viral Budding From Plasma Membrane Lysosomal Membrane Organization Regulation Of Centrosome Cycle Late Endosome To Lysosome Transport Kinetochore Microtubule Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Viral Budding Nuclear Membrane Reassembly Multivesicular Body Membrane Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Assembly Multivesicular Body Organization Regulation Of Spindle Assembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Multivesicular Body Mitotic Metaphase Chromosome Alignment Multivesicular Body Sorting Pathway Regulation Of Centrosome Duplication Nuclear Membrane Organization Autophagosome Maturation Regulation Of Cell Cycle Process Regulation Of Cell Cycle Autophagosome Membrane Metaphase Chromosome Alignment Membrane Assembly Midbody Chromosome Localization Endosome Organization Nuclear Pore Nucleus Organization Vesicle Fusion Organelle Membrane Fusion Regulation Of Microtubule-based Process Plasma Membrane Organization Lysosomal Transport	Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Midbody Abscission Mitotic Cytokinetic Process Viral Budding Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Cytokinetic Process Viral Budding From Plasma Membrane Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Lysosome Transport Protein-containing Complex Disassembly Regulation Of Mitotic Spindle Assembly Nuclear Membrane Reassembly Chromosome Localization Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Release From Host Cell Endosome Organization Nuclear Pore Nucleus Organization Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization ESCRT III Complex Disassembly ESCRT Complex Disassembly Membrane Fission Mitotic Metaphase Chromosome Alignment ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Multivesicular Body Nuclear Membrane Organization Multivesicular Body-lysosome Fusion Autophagosome Maturation Lysosomal Membrane Organization Metaphase Chromosome Alignment Membrane Assembly Viral Process Late Endosome Membrane Autophagy Kinetochore Endosome Vacuolar Transport Kinetochore Microtubule Midbody Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Membrane Membrane Coat Endosomal Transport
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