PCP2 and MEOX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PCP2	MEOX1
Description		Purkinje cell protein 2	mesenchyme homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Regulator Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	G Protein-coupled Opsin Signaling Pathway	Somite Specification Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development
Pathways		G alpha (i) signalling events
Drugs
Diseases
GWAS		Neuropathic pain in head and neck cancer ( 29884837)	Fractures ( 30158200)
Interacting Genes		4 interacting genes: GNAI1 GNAI2 GNAI3 MEOX1	99 interacting genes: ACBD4 ACOT12 AIRIM ALOX5 ANAPC2 APP APPL1 ATG9A BANP BNIP2 BYSL C14orf119 C1orf50 CACNB3 CATSPERT CCDC102B CDC34 CIAO1 CIB3 CIMIP4 CKS1B CNOT11 CSNK2A1 CWF19L2 CYFIP1 DCX DNAAF19 DUSP3 EIF4A3 EIF4EBP1 EMD FMR1 GCC1 GEMIN2 GPANK1 GYS1 HMBOX1 HMGB3 HOMER3 HOXC8 HYCC2 INPP5J KANK2 KCTD7 L3MBTL2 LMNA MAPK9 MBD3 MCRS1 MEF2A MID1 MID2 MKRN3 MLX MORF4L1 MVP NAGK NDOR1 NEIL2 OSGIN1 PAGE3 PARVG PAX1 PAX3 PCP2 PDE4C PELI2 PIN1 PLCD4 PM20D2 POLR3GL PPM1F PRKAG1 PRKN QRICH1 RAD52 RANBP3 RBM41 RBM5 SDCBP SEC14L4 SOX10 SPAG8 SPIC SYT17 TCEANC TCP11L1 TRAPPC2L TRIM41 TRIML2 TRIP10 TXLNA TXNL4B UBE2R2 UBXN2B UBXN7 UNC45A ZCCHC10 ZNF410
Entrez ID		126006	4222
HPRD ID		18723	02537
Ensembl ID		ENSG00000174788	ENSG00000005102
Uniprot IDs		Q8IVA1	P50221
PDB IDs
Enriched GO Terms of Interacting Partners?		Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex G Protein-coupled Receptor Binding Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Midbody Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway GTPase Activity Ciliary Basal Body GTP Binding Cell Division GDP Binding Centrosome G Protein-coupled Receptor Signaling Pathway Centriolar Satellite Negative Regulation Of Secretion By Cell Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Catalytic Activity D2 Dopamine Receptor Binding Negative Regulation Of Secretion Positive Regulation Of Relaxation Of Smooth Muscle G Protein-coupled Serotonin Receptor Binding Sclerotome Development Adenylate Cyclase Inhibitor Activity Adenylate Cyclase Regulator Activity Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Somite Specification Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Metabolic Process Regulation Of Protein Localization To Cell Cortex Negative Regulation Of Calcium Ion-dependent Exocytosis G Protein-coupled Adenosine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Cytoskeleton Positive Regulation Of Urine Volume Lysosomal Membrane HMG Box Domain Binding Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Nucleotide Binding Cellular Response To Forskolin Negative Regulation Of Transport Regulation Of Relaxation Of Muscle Segment Specification Somite Development Response To Forskolin Positive Regulation Of Cholesterol Biosynthetic Process G Protein-coupled Serotonin Receptor Signaling Pathway Purinergic Nucleotide Receptor Signaling Pathway Regulation Of Urine Volume	Protein Binding Cytosol Nucleoplasm Cytoplasm Growth Cone Filopodium Spindle Pole Centrosome Translation Repressor Activity Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Identical Protein Binding Perinuclear Region Of Cytoplasm Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Translation At Postsynapse
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