FMR1 and FXR1

Number of citations of the paper that reports this interaction (PMID 8668200)
56

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		FMR1	FXR1
Gene Name		fragile X mental retardation 1	fragile X mental retardation, autosomal homolog 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm MRNA Cap Binding Complex Microtubule Cytoplasmic Stress Granule Membrane Cytoplasmic Ribonucleoprotein Granule Polysomal Ribosome Dendritic Spine Dendritic Shaft Cell Body Synapse Neuronal Ribonucleoprotein Granule	Nucleolus Cytoplasm Polysome Membrane Costamere
	Molecular Function	RNA Binding MRNA Binding Protein Binding Microtubule Binding Poly(A) RNA Binding	G-quadruplex RNA Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Poly(A) RNA Binding
	Biological Process	Central Nervous System Development Negative Regulation Of Translation Negative Regulation Of Translational Initiation MRNA Transport	Apoptotic Process Muscle Organ Development Negative Regulation Of Translation Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956)	Schizophrenia ( 19571811)
Protein-Protein Interactions		15 interactors: CYFIP1 CYFIP2 FSD2 FXR1 FXR2 INCA1 MEOX1 NCL NUFIP1 NUFIP2 RANBP9 SPAG5 STAU1 UBE2I YBX1	11 interactors: C14orf1 CRMP1 CSNK2A1 CYFIP2 FMR1 FXR2 GBP2 KIAA1377 LRIF1 LUC7L2 PRSS23
Entrez ID		2332	8087
HPRD ID		02398	02892
Ensembl ID		ENSG00000102081	ENSG00000114416
Uniprot IDs		G3V0J0 G8JL90 G8JLE9 Q06787 Q8IXW7 R9WQY1	B4DXZ6 E9PFF5 P51114
PDB IDs		2BKD 2FMR 2LA5 2QND	2CPQ 3KUF 3O8V
Enriched GO Terms of Interacting Partners?		Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Translation Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Positive Regulation By Virus Of Viral Protein Levels In Host Cell Box C/D SnoRNP Assembly Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Process Sclerotome Development CRD-mediated MRNA Stabilization Somite Specification Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Actin Nucleation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase I Promoter Intracellular MRNA Localization Chromosome Segregation Positive Regulation Of Macromolecule Biosynthetic Process Hematopoietic Stem Cell Differentiation Positive Regulation Of Gene Expression Regulation Of Gene Expression
Tagcloud ?		17beta cav1 caveolae caveolin cgg cingulate copyright coupling demonstration electrophysiological eralpha facilitation fear fmrp fragile fxs glua1 inherited interacted ko plasticity potentiation raft recording rescued reserved retardation rights shrna	address adhesion arm comprised coprecipitated cytoplasm cytoplasmic desmoplakin desmosomes destabilized g3bp gain mrnas outside pabpc1 particles pkp1 pkp2 pkp3 plakophilins posttranscriptional regulators repeat ribonucleoprotein rnase serve stabilized unaffected upf1
Tagcloud (Difference) ?		17beta cav1 caveolae caveolin cgg cingulate copyright coupling demonstration electrophysiological eralpha facilitation fear fmrp fragile fxs glua1 inherited interacted ko plasticity potentiation raft recording rescued reserved retardation rights shrna	address adhesion arm comprised coprecipitated cytoplasm cytoplasmic desmoplakin desmosomes destabilized g3bp gain mrnas outside pabpc1 particles pkp1 pkp2 pkp3 plakophilins posttranscriptional regulators repeat ribonucleoprotein rnase serve stabilized unaffected upf1
Tagcloud (Intersection) ?