FMR1 and NUFIP1

Number of citations of the paper that reports this interaction (PMID 10556305)
20

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		FMR1	NUFIP1
Gene Name		fragile X mental retardation 1	nuclear fragile X mental retardation protein interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm MRNA Cap Binding Complex Microtubule Cytoplasmic Stress Granule Membrane Cytoplasmic Ribonucleoprotein Granule Polysomal Ribosome Dendritic Spine Dendritic Shaft Cell Body Synapse Neuronal Ribonucleoprotein Granule	Nucleus Nucleoplasm Perichromatin Fibrils Nucleolus Transcription Elongation Factor Complex Nuclear Matrix Cytosolic Ribosome Protein Complex Presynaptic Active Zone Pre-snoRNP Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Microtubule Binding Poly(A) RNA Binding	DNA Binding RNA Binding Protein Binding SnoRNA Binding Protein Binding, Bridging Identical Protein Binding Metal Ion Binding
	Biological Process	Central Nervous System Development Negative Regulation Of Translation Negative Regulation Of Translational Initiation MRNA Transport	Box C/D SnoRNP Assembly RNA Processing Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956)	Oleic acid (18:1n-9) plasma levels ( 23362303)
Protein-Protein Interactions		15 interactors: CYFIP1 CYFIP2 FSD2 FXR1 FXR2 INCA1 MEOX1 NCL NUFIP1 NUFIP2 RANBP9 SPAG5 STAU1 UBE2I YBX1	7 interactors: BRCA1 CCNT1 FMR1 KLF6 RUVBL1 RUVBL2 TAF9
Entrez ID		2332	26747
HPRD ID		02398	05073
Ensembl ID		ENSG00000102081	ENSG00000083635
Uniprot IDs		G3V0J0 G8JL90 G8JLE9 Q06787 Q8IXW7 R9WQY1	Q9UHK0
PDB IDs		2BKD 2FMR 2LA5 2QND
Enriched GO Terms of Interacting Partners?		Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Translation Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Positive Regulation By Virus Of Viral Protein Levels In Host Cell Box C/D SnoRNP Assembly Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Process Sclerotome Development CRD-mediated MRNA Stabilization Somite Specification Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Actin Nucleation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase I Promoter Intracellular MRNA Localization Chromosome Segregation Positive Regulation Of Macromolecule Biosynthetic Process Hematopoietic Stem Cell Differentiation Positive Regulation Of Gene Expression Regulation Of Gene Expression	Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process DNA Recombination Peptidyl-lysine Modification Cellular Response To DNA Damage Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Histone Acetylation Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone H4 Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Histone Modification Transcription, DNA-templated Positive Regulation Of Histone Modification RNA Biosynthetic Process DNA Duplex Unwinding DNA Geometric Change Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Organic Substance DNA-templated Transcription, Elongation Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process DNA Repair Cellular Response To Stress Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		17beta cav1 caveolae caveolin cgg cingulate copyright coupling demonstration electrophysiological eralpha facilitation fear fmrp fragile fxs glua1 inherited interacted ko plasticity potentiation raft recording rescued reserved retardation rights shrna
Tagcloud (Difference) ?		17beta cav1 caveolae caveolin cgg cingulate copyright coupling demonstration electrophysiological eralpha facilitation fear fmrp fragile fxs glua1 inherited interacted ko plasticity potentiation raft recording rescued reserved retardation rights shrna
Tagcloud (Intersection) ?