FMR1

Gene Name		fragile X mental retardation 1
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm MRNA Cap Binding Complex Microtubule Cytoplasmic Stress Granule Membrane Cytoplasmic Ribonucleoprotein Granule Polysomal Ribosome Dendritic Spine Dendritic Shaft Cell Body Synapse Neuronal Ribonucleoprotein Granule
	Molecular Function	RNA Binding MRNA Binding Protein Binding Microtubule Binding Poly(A) RNA Binding
	Biological Process	Central Nervous System Development Negative Regulation Of Translation Negative Regulation Of Translational Initiation MRNA Transport
Pathways
Drugs
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956)
Protein-protein Interactions		15 interactors: CYFIP1 CYFIP2 FSD2 FXR1 FXR2 INCA1 MEOX1 NCL NUFIP1 NUFIP2 RANBP9 SPAG5 STAU1 UBE2I YBX1
Entrez ID		2332
HPRD ID		02398
Ensembl ID		ENSG00000102081
Uniprot IDs		G3V0J0 G8JL90 G8JLE9 Q06787 Q8IXW7 R9WQY1
PDB IDs		2BKD 2FMR 2LA5 2QND
Enriched GO Terms of Interacting Partners?		Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Translation Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Positive Regulation By Virus Of Viral Protein Levels In Host Cell Box C/D SnoRNP Assembly Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Process Sclerotome Development CRD-mediated MRNA Stabilization Somite Specification Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Actin Nucleation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase I Promoter Intracellular MRNA Localization Chromosome Segregation Positive Regulation Of Macromolecule Biosynthetic Process Hematopoietic Stem Cell Differentiation Positive Regulation Of Gene Expression Regulation Of Gene Expression
Tagcloud ?		17beta cav1 caveolae caveolin cgg cingulate copyright coupling demonstration electrophysiological eralpha facilitation fear fmrp fragile fxs glua1 inherited interacted ko plasticity potentiation raft recording rescued reserved retardation rights shrna