UBE2J2 and ATP13A2

Number of citations of the paper that reports this interaction (PMID 22645275)
9

Data Source:
BioGRID (two hybrid)

		UBE2J2	ATP13A2
Gene Name		ubiquitin-conjugating enzyme E2, J2	ATPase type 13A2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Lysosome Lysosomal Membrane Integral Component Of Membrane
	Molecular Function	ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity	Protein Binding ATP Binding ATPase Activity Metal Ion Binding
	Biological Process	Protein Polyubiquitination Response To Unfolded Protein ER-associated Ubiquitin-dependent Protein Catabolic Process	Cation Transport Metabolic Process Cellular Response To Manganese Ion
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Height ( 20189936)
Protein-Protein Interactions		11 interactors: ATP13A2 HERC4 ITCH MGRN1 NEDD4L RNF10 TRIM25 UBC UBE2G2 WWP2 XIAP	36 interactors: ACKR3 ATP5G2 CCKBR CMTM6 COL1A1 CXCR4 CYGB DCAF7 EMC7 F2R FAM111B FAM192A FAM8A1 FKBP8 FUNDC2 GPR21 HIPK1 ICAM2 LMAN2 LRP6 MEX3B MYCBP2 NPY1R NRXN1 OCA2 OSTC PCDHB10 PCMTD2 PDIA6 SEC61B SPCS2 TSPAN14 UBE2J2 VAMP2 WDR5B WDR83OS
Entrez ID		118424	23400
HPRD ID		15600	13677
Ensembl ID		ENSG00000160087	ENSG00000159363
Uniprot IDs		A6NGS0 Q8N2K1	Q9NQ11
PDB IDs		2F4W
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Negative Regulation Of Type I Interferon Production Viral Life Cycle Viral Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Type I Interferon Production Proteolysis Catabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Protein K63-linked Ubiquitination Negative Regulation Of Cytokine Production Positive Regulation Of Protein Catabolic Process Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Transporter Activity Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Viral Entry Into Host Cell Regulation Of Innate Immune Response Entry Into Host Cell Protein Autoubiquitination Regulation Of Potassium Ion Transport Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Protein Linear Polyubiquitination Positive Regulation Of Caveolin-mediated Endocytosis Interaction With Host Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Signaling Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity See more	Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Protein Localization To Membrane Embryonic Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Membrane Regulation Of Signaling Establishment Of Protein Localization Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Localization Membrane Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cardiovascular System Development Synaptic Transmission Motor Neuron Axon Guidance Cell-cell Signaling Locomotion Positive Regulation Of Signal Transduction Chemotaxis Face Morphogenesis Embryonic Camera-type Eye Morphogenesis ER-associated Ubiquitin-dependent Protein Catabolic Process Head Morphogenesis Positive Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Canonical Wnt Signaling Pathway Involved In Cardiac Neural Crest Cell Differentiation Involved In Heart Development Negative Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure Negative Regulation Of Planar Cell Polarity Pathway Involved In Outflow Tract Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Pericardium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Right Atrium Morphogenesis Negative Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Ventricular Septum Morphogenesis Cellular Response To Fluoride Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Tyrosine Transport Synapse Organization Protein Localization To Nucleus Embryonic Eye Morphogenesis Cellular Protein Localization Regulation Of Protein Secretion Cellular Metal Ion Homeostasis Response To External Stimulus Cellular Homeostasis Cerebellum Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Face Development Regulation Of Signal Transduction Cellular Protein Metabolic Process Regulation Of Insulin Secretion See more
Tagcloud ?		abolished alter conjugating degradation disrupt ectopic enzyme er inactivated incubation localization mammalian pharmacological proteasomal proteasome regulating second state steady transfected truncated ubc ubcs ubiquitin ubiquitination unfolded unstable upr	ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?		abolished alter conjugating degradation disrupt ectopic enzyme er inactivated incubation localization mammalian pharmacological proteasomal proteasome regulating second state steady transfected truncated ubc ubcs ubiquitin ubiquitination unfolded unstable upr	ataxin atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa lyst machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?