UBE2J2 and UBE2G2

Number of citations of the paper that reports this interaction (PMID 8393731)
140

Data Source:
HPRD (in vivo)

		UBE2J2	UBE2G2
Gene Name		ubiquitin-conjugating enzyme E2, J2	ubiquitin-conjugating enzyme E2G 2
Image
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Cytosol
	Molecular Function	ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Response To Unfolded Protein ER-associated Ubiquitin-dependent Protein Catabolic Process	Ubiquitin-dependent Protein Catabolic Process Protein N-linked Glycosylation Via Asparagine ER-associated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ATP13A2 HERC4 ITCH MGRN1 NEDD4L RNF10 TRIM25 UBC UBE2G2 WWP2 XIAP	37 interactors: AMFR ARL14 BIRC8 CBL CNNM3 CPOX CUL9 FARP2 HBS1L HERPUD1 KDM2A KIAA0368 MDM2 MGRN1 MLLT6 MUL1 NDUFS4 PARK2 POLR3F RBX1 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		118424	7327
HPRD ID		15600	04387
Ensembl ID		ENSG00000160087	ENSG00000184787
Uniprot IDs		A6NGS0 Q8N2K1	P60604
PDB IDs		2F4W	2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Negative Regulation Of Type I Interferon Production Viral Life Cycle Viral Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Type I Interferon Production Proteolysis Catabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Protein K63-linked Ubiquitination Negative Regulation Of Cytokine Production Positive Regulation Of Protein Catabolic Process Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Transporter Activity Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Viral Entry Into Host Cell Regulation Of Innate Immune Response Entry Into Host Cell Protein Autoubiquitination Regulation Of Potassium Ion Transport Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Protein Linear Polyubiquitination Positive Regulation Of Caveolin-mediated Endocytosis Interaction With Host Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Signaling Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Protein Ubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Polyubiquitination Catabolic Process Proteolysis Cellular Protein Metabolic Process Cellular Protein Modification Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein K48-linked Ubiquitination Protein Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Cellular Response To Stress Cellular Metabolic Process Regulation Of Proteolysis Regulation Of Signaling Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Signal Transduction Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Protein Ubiquitination Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Signal Transduction Protein K63-linked Ubiquitination Cellular Response To Topologically Incorrect Protein Negative Regulation Of Mitochondrial Fusion Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Signaling Regulation Of Mitochondrial Fusion Protein Autoubiquitination Response To Stimulus Response To Unfolded Protein Regulation Of Protein Stability Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Catabolic Process Cellular Response To Stimulus Response To Organic Substance Positive Regulation Of Mitochondrial Fission Regulation Of Intracellular Signal Transduction Response To Stress Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		abolished alter conjugating degradation disrupt ectopic enzyme er inactivated incubation localization mammalian pharmacological proteasomal proteasome regulating second state steady transfected truncated ubc ubcs ubiquitin ubiquitination unfolded unstable upr	alters assembly attack bond catalyzes chain chains cooperative cooperatively correct cue distal donor drive e3 elusive g2br gp78 helps lys48 monoubiquitin orientation polyubiquitin preassembled preferential thioester transferring ubiquitin
Tagcloud (Difference) ?		abolished alter conjugating degradation disrupt ectopic enzyme er inactivated incubation localization mammalian pharmacological proteasomal proteasome regulating second state steady transfected truncated ubc ubcs ubiquitination unfolded unstable upr	alters assembly attack bond catalyzes chain chains cooperative cooperatively correct cue distal donor drive e3 elusive g2br gp78 helps lys48 monoubiquitin orientation polyubiquitin preassembled preferential thioester transferring
Tagcloud (Intersection) ?		ubiquitin